Antihistamines for Allergic Rhinitis

 

Older (first-generation) over-the-counter and prescription antihistamines

Generic Name Brand Name
acrivastine Semprex-D (prescription)
brompheniramine maleate
chlorpheniramine maleate Chlor-Trimeton (otc)
clemastine fumarate Tavist-1 (prescription)
diphenhydramine hydrochloride Benadryl (otc)
hydroxyzine hydrochloride Vistaril (prescription)
promethazine hydrochloride

Newer (second-generation) over-the-counter antihistamines

Generic Name Brand Name
cetirizine hydrochloride Zyrtec (prescription)
loratadine Alavert (prescription), Claritin (prescription)

Newer (second-generation) prescription antihistamines

Generic Name Brand Name
azelastine Astelin (prescription)
desloratadine Clarinex (prescription)
fexofenadine hydrochloride Allegra (prescription)
levocetirizine Xyzal (prescription)
olopatadine Patanase (prescription)

Antihistamines may be available as tablets, capsules, nasal sprays, or liquids. You can use them alone or combined with decongestants to treat allergic rhinitis.

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