Antioxidants and Free Radicals

 
Antioxidants and Free Radicals

Antioxidants are nutrients that help minimize free-radical damage to the body. Free radicals are highly reactive compounds that are created in the body during normal metabolic functions or introduced from the environment, such as by exposure to pollution and other toxins. Inherently unstable, free radicals contain “extra” energy which they try to reduce by reacting with certain chemicals in the body, which interferes with the cells’ ability to function normally. Antioxidants combat free radicals in several ways: they may reduce the energy of the free radical, stop the free radical from forming in the first place, or interrupt an oxidizing chain reaction to minimize the damage caused by free radicals.

ANTIOXIDANTS

Consuming a wide variety of antioxidant enzymes, vitamins, minerals, and herbs may be the best way to provide the body with the most complete protection against free-radical damage.

  • The body produces several antioxidant enzymes, including superoxide dismutase, catalase, and glutathione peroxidase, that neutralize many types of free radicals. Supplements of these enzymes are available for oral administration. However, their absorption is probably minimal at best. Supplementing with the “building blocks” the body requires to make superoxide dismutase, catalase, and glutathione peroxidase may be more effective. These building block nutrients include the minerals manganese, zinc, and copper for superoxide dismutase and selenium for glutathione peroxidase.
  • In addition to enzymes, many vitamins and minerals act as antioxidants in their own right, such as vitamin C, vitamin E, beta-carotene, lutein, lycopene, vitamin B2, coenzyme Q10, and cysteine (an amino acid). Herbs, such as bilberry, turmeric (curcumin), grape seed or pine bark extracts, and ginkgo can also provide powerful antioxidant protection for the body.
  • An increasing number of antioxidant-rich "superfoods" are available, including mangosteen, kombucha, açaí, pomegranate, goji berry, and chia seed.

FREE RADICALS

Free radicals are believed to play a role in more than sixty different health conditions, including the aging process, cancer, and atherosclerosis. Reducing exposure to free radicals and increasing intake of antioxidant nutrients has the potential to reduce the risk of free radical-related health problems.

Oxygen, although essential to life, is the source of the potentially damaging free radicals. Free radicals are also found in the environment. Environmental sources of free radicals include exposure to ionizing radiation (from industry, sun exposure, cosmic rays, and medical X-rays), ozone and nitrous oxide (primarily from automobile exhaust), heavy metals (such as mercury, cadmium, and lead), cigarette smoke (both active and passive), alcohol, unsaturated fat, and other chemicals and compounds from food, water, and air.

Also indexed as:
  • antioxidant,
  • free radical,
  • oxygen free radical

About this treatment

Interactions with Supplements, Foods, & Other Compounds

At the time of writing, there were no well-known interactions with this supplement.

Interactions with Medicines

Certain medicines interact with this supplement.

May Be Beneficial:Some medicines may increase the need for this supplement.
Avoid:Some medicines interact with this supplement, so they should not be taken together.
Check: Some interactions between this supplement and certain medicines require more explanation. Click the link to see details.

Note: The following list only includes the generic or class name of a medicine. To find a specific brand name, use the Medicines Index.

May Be Beneficial:Docetaxel
May Be Beneficial:Fluorouracil
May Be Beneficial:Paclitaxel
Check: Bicalutamide
Check: Busulfan
Check: Capecitabine
Check: Carboplatin
Check: Carmustine
Check: Chlorambucil
Check: Cisplatin
Check: Cladribine
Check: Cyclophosphamide
Check: Cytarabine
Check: Floxuridine
Check: Fludarabine
Check: Fluorouracil
Check: Ifosfamide
Check: Lomustine
Check: Mechlorethamine
Check: Melphalan
Check: Mercaptopurine
Check: Polifeprosan 20 with Carmustine
Check: Streptozocin
Check: Thioguanine
Check: Thiotepa
Check: Uracil Mustard
Check: Valproate

Last Review: 05-11-2011

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The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2011.

© 1995-2011 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated. This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

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