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Aspirin - References
Aspirin is a drug that reduces swelling, pain, and fever. In recent years, long-term low-dose aspirin has been recommended to reduce the risk of heart attacks and strokes. In the future aspirin may be recommended to reduce the risk of some cancers. Reye’s syndrome, a rare but serious illness affecting children and teenagers, has been associated with aspirin use. To prevent Reye’s syndrome, people should consult their doctor and/or pharmacist before giving aspirin, aspirin-containing products, or herbs containing salicylates to children and teenagers.
Summary of Interactions with Vitamins, Herbs, & Foods
 May Be Beneficial: Depletion or interference—This medication may deplete these substances from the body or interfere with how they work; extra intake may help replenish them. | Iron Vitamin C Zinc Folic Acid* Vitamin B12* |
| May Be Beneficial: Side effect reduction and/or prevention—These substances may help reduce the likelihood and/or severity of a potential side effect caused by the medication.
| none |
| May Be Beneficial: Supportive interaction—These substances may help this medication work better. | Cayenne Licorice |
 Avoid: Reduces drug effectiveness—When taking this medication, avoid these substances as they may decrease the medication's absorption and/or activity in the body. | none |
| Avoid: Adverse interaction—When taking this medication, avoid these substances, as the combination may cause undesirable or dangerous interactions. | Ginkgo Vitamin E Coleus* |
 Check: Explanation needed—When taking this medication, read the article details and discuss them with your doctor or pharmacist before taking these substances. | none |
An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.
Also indexed as:
- acetylsalicylic acid,
- ASA,
- Aspergum,
- Aspergum Cherry,
- Aspergum Orginal,
- aspirin,
- Bayer,
- Bayer aspirin,
- Bayer Low Strength,
- Halfprin,
- Norwich Aspirin,
- St. Joseph aspirin,
- Zorprin
About this treatment
1. Buist RA. Drug-nutrient interactions—an overview. Intl Clin Nutr Rev 1984;4(3):114 [review].
2. Alter HJ, Zvaifler MJ, Rath CE. Interrelationship of rheumatoid arthritis, folic acid and aspirin. Blood 1971;38:405–16.
3. Van Oijen MGH, Laheij RJF, Peters WHM, et al. Association of aspirin use with vitamin B12 deficiency (results of the BACH study). Am J Cardiol 2004;94:975–7.
4. Coffey G, Wilson CWM. Ascorbic acid deficiency and aspirin-induced haematemesis. BMJ 1975;I:208.
5. Kim JM, White RH. Effect of vitamin E on the anticoagulant response to warfarin. Am J Cardiol 1996;77:545–6.
6. Liede KE, Haukka JK, Saxén LM, Heinon OP. Increased tendency towards gingival bleeding caused by joint effect of alpha-tocopherol supplementation and acetylsalicylic acid. Ann Med 1998;30:542–6.
7. Ambanelli U, Ferraccioli GF, Serventi G, Vaona GL. Changes in serum and urinary zinc induced by ASA and indomethacin. Scand J Rheumatol 1982;11:63–4.
8. Abdel Salam OME, Mószik G, Szolcsányi J. Studies on the effect of intragastric capsaicin on gastric ulcer and on the prostacyclin-induced cytoprotection in rats. Pharmacol Res 1995;32:209–15.
9. Holzer P, Pabst MA, Lippe IT. Intragastric capsaicin protects against aspirin-induced lesion formation and bleeding in the rat gastric mucosa. Gastroenterology 1989;96:1425–33.
10. Yeoh KG, Kang JY, Yap I, et al. Chili protects against aspirin-induced gastroduodenal mucosal injury in humans. Dig Dis Sci 1995;40:580–3.
11. Matthews MK. Association of Ginkgo biloba with intracerebral hemorrhage [letter]. Neurology 1998;50:1933.
12. Rosenblatt M, Mindell J. Spontaneous hyphema associated with ingestion of Ginkgo biloba extract [letter]. N Engl J Med 1997;336:1108.
13. Rees WDW, Rhodes J, Wright JE, et al. Effect of deglycyrrhizinated liquorice on gastric mucosal damage by aspirin. Scand J Gastroenterol 1979;14:605–7.
14. Morgan AG, McAdam WAF, Pascoo C, Darnborough A. Comparison between cimetidine and Caved-S in the treatment of gastric ulceration, and subsequent maintenance therapy. Gut 1982;23:545–51.
15. Bennett A, Clark-Wibberley T, et al. Aspirin-induced gastric mucosal damage in rats: Cimetidine and deglycyrrhizinated liquorice together give greater protection than low doses of either drug alone. J Pharm Pharmacol 1980;32:151.
Last Review: 05-11-2011
Copyright © 2011 Aisle7. All rights reserved. www.Aisle7.net
Please read the disclaimer about the limitations of the information provided here. Do NOT rely solely on the information in this article. The Aisle7 knowledgebase does not contain every possible interaction.
Learn more about Aisle7, the company.
The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2011.
© 1995-2011 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated. This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.
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