Picture of normal artery and artery narrowed by atherosclerosis

Atherosclerosis, sometimes called “hardening of the arteries,” occurs when cholesterol, calcium, and other substances build up in the inner lining of the arteries, forming a material called plaque. Over time, plaque buildup narrows the artery and blocks blood flow through it.

ByHealthwise Staff
Primary Medical ReviewerE. Gregory Thompson, MD - Internal Medicine
Specialist Medical ReviewerJohn A. McPherson, MD, FACC, FSCAI - Cardiology
Last RevisedMay 1, 2010

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