Beta-Glucan

 
Beta-Glucan

Beta-glucan is a fiber-type complex sugar (polysaccharide) derived from the cell wall of baker’s yeast, oat and barley fiber, and many medicinal mushrooms, such as maitake. In their natural states, yeast and mushrooms contain a mixture of beta-1,3-glucan and beta-1,6-glucan. Oats and barley contain a mixture of beta-1,3-glucan and beta-1,4-glucan. In addition to purified beta-1,3-glucan from these sources, you may see products listed as beta-1,3/1,6-glucan in the case of yeast-derived products and as beta-1,3/1,4-glucan when derived from oats. Similar (if not identical) properties have been shown for beta-glucan-rich extracts and purified beta-glucan derived from oats, baker’s yeast, and mushrooms.

What Are "Star" Ratings?

a7_3star Reliable and relatively consistent scientific data showing a substantial health benefit.

a7_2star Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.

a7_1star For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:


Used for AmountWhy
High Cholesterol
2,900 to 15,000 mg daily3 stars Beta-glucan is a type of soluble fiber that has been shown to lower total and LDL (“bad”) cholesterol and raise HDL (“good”) cholesterol.

3 stars High Cholesterol

2,900 to 15,000 mg daily

Beta-glucan is a type of soluble fiber molecule derived from the cell wall of baker’s yeast, oats and barley, and many medicinal mushrooms, such as maitake. Beta-glucan is the key factor for the cholesterol-lowering effect of oat bran.1, 2, 3, 4 As with other soluble-fiber components, the binding of cholesterol (and bile acids) by beta-glucan and the resulting elimination of these substances in the feces is very helpful for reducing blood cholesterol.5, 6, 7 Results from a number of double-blind trials with either oat- or yeast-derived beta-glucan indicate typical reductions, after at least four weeks of use, of approximately 10% for total cholesterol and 8% for LDL (“bad”) cholesterol, with elevations in HDL (“good”) cholesterol ranging from zero to 16%.8, 9, 10, 11, 12 For lowering cholesterol levels, the amount of beta-glucan used has ranged from 2,900 to 15,000 mg per day.

Used for AmountWhy
Liver Cirrhosis
(Inulin, Pectin, Resistant Starch)
10 grams total fermentable fiber daily2 stars In a study of people with cirrhosis, supplementing with fermentable fiber (containing equal parts of beta-glucan, inulin, pectin, and resistant starch) improved liver and brain function.

2 stars Liver Cirrhosis

10 grams total fermentable fiber daily

In a study of people with cirrhosis, supplementing with 10 grams of fermentable fiber per day (containing equal parts of beta-glucan, inulin, pectin, and resistant starch) for 30 days resulted in an improvement in liver function.13 The impaired brain function that often accompanies cirrhosis of the liver (hepatic encephalopathy) also improved.


Used for AmountWhy
Immune Function
Refer to label instructions 1 star Beta-glucan activates white blood cells, which in turn can recognize and kill tumor cells, correct oxidative damage, and speed up recovery of damaged tissue.

1 star Immune Function

Beta-glucan is a fiber-type polysaccharide (complex sugar) derived from the cell wall of baker’s yeast, oat and barley fiber, and many medicinal mushrooms, such as maitake. Numerous experimental studies in test tubes and animals have shown beta-glucan to activate white blood cells.14, 15, 16, 17, 18 In fact, there have been hundreds of research papers on beta-glucan since the 1960s.19 The research indicates that beta-1,3-glucan, in particular, is very effective at activating white blood cells known as macrophages and neutrophils. A beta-glucan–activated macrophage or neutrophil can recognize and kill tumor cells, remove cellular debris resulting from oxidative damage, speed up recovery of damaged tissue, and further activate other components of the immune system.20, 21 Although the research in test tube and animal studies is promising, many questions remain about the effectiveness of beta-glucan as an oral supplement to enhance immune function in humans. Controlled trials are necessary to determine whether humans can benefit from beta-glucan, and in what amounts oral beta-glucan must be taken from meaningful effects.
Also indexed as:
  • beta-glucan

About this treatment

How to Use It

For lowering cholesterol levels, the amount of beta-glucan used in clinical trials has ranged from 2,900 to 15,000 mg per day. For enhancing immune function, an effective amount has not yet been determined due to the lack of studies in this application. However, manufacturers of beta-glucan products usually recommend between 50 and 1,000 mg daily (to be taken on an empty stomach), although some products contain as much as 500 mg per capsule.

Where to Find It

Beta-glucan is found in the cell walls of many yeast and cereal fibers, such as oats, wheat, and barley. As a dietary supplement, beta-glucan is available in liquid form as well as in capsules and tablets.

Possible Deficiencies

Because beta-glucan is not an essential nutrient, deficiencies do not occur.


Last Review: 05-11-2011

LogoCpyrt.gif

Copyright © 2011 Aisle7. All rights reserved. www.Aisle7.net

Learn more about Aisle7, the company.

The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2011.

© 1995-2011 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated. This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

Advertisement
Care Circle

It Seems That You Are Not Logged In...

OR

Join Now

Welcome to Care Circle, an exclusive tool to help you take care of yourself and your loved ones. Here's how it works:

  1. Create profiles for yourself and your loved ones.
  2. Select the topics and conditions that interest each of you.
  3. Get customized news updates, original content, tools, and expert advice for each Care Circle member delivered directly to your personalized homepage.

The information you input is strictly private; you choose who has access to your Care Circle.

How do I add myself or someone else to my care circle?

Click on "Add someone." Fill out the short profile. Choose an avatar. Select the topics and conditions that interest this person from the pulldown menu. You can select as many as you want, but you must choose at least one. Click on "Add Someone" again. You should start getting updates immediately.

How do I save content to my Care Circle?

Click on "Manage My Care Circle." Select the tab of the person for whom you're saving content. Put your cursor over the piece of content that you want to save; a disk icon will appear in the righthand corner. Click on the disk and the piece of content will be moved to a save folder.

How do I add additional topics and conditions for someone in my Care Circle?

Click on "Manage My Care Circle." Select the tab for the person whose preferences you'd like to update. Under "Add More to Follow," select additional topics and conditions.

How do I delete topics and conditions for someone in my Care Circle?

Click on "Manage My Care Circle." Select the tab for the person whose preferences you'd like to update. Under "Follows," scroll over the topic or condition you want to delete. An "X" should appear on the righthand side. Click on the "X" and the topic or condition will be deleted from the list.