Charlie Sheen (pictured on March 29 in N.Y.C.) has struggled with substance abuse issues throughout his career, but things truly came to a head when he was admitted to rehab multiple times in 2010 and Warner Bros. subsequently fired him from his eight-season-long stint on CBS' hit sitcom Two and a Half Men. That's when Sheen had a full-blown meltdown -- dating "goddesses," going on a widely-panned concert tour, publicly feuding with Men creator Chuck Lorre, and declaring that he was "winning," had "Adonis DNA" and was a "Vatican warlock assassin." But just when we were about to write Sheen off, he poked fun at himself at his Comedy Central roast back in September, landed a deal to star in the FX sitcom Anger Management and stopped shooting off his mouth in public. In advance of the June 28 premiere of Anger Management, Sheen has embarked on a mea-culpa media blitz, apologzing for his "cringeable" behavior and admitting to Rolling Stone that he was "in total denial." If his new show catches on, Sheen will have made a miraculous comeback -- in record time!