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Sheen, whose new comedy debuts on FX June 28, told the Times he's been acting for more than 30 years and that "there's a lot more out there to do than make-believe, you know?"
The 46-year-old actor explained that he loves what television has provided him, but he knows that there's no guarantee lightning will strike twice and make his new series a hit.
"I mean, I’m grateful," he said. "I've got a dream life as a direct result of television, you know? But at some point you just get tired of wearing somebody else's clothes, saying somebody else’s words and working in somebody else's space. I'm also aware of the fact that you don't get these kinds of shots in the same lifetime. You’re only supposed to have one hit show, unless you're Kelsey Grammer."
And Sheen already has his post-acting life planned out, and it doesn't involve hard partying and lots of ladies. Sheen says he wants a simpler life.
"When I'm done with this business it's just going to be about soccer games and amusement parks," he added, referring to his children with ex-wives Denise Richards and Brooke Mueller. "And when this ends, I’m done. This is my swan song."