When: Sundays at 10:30 p.m. on HBO; premiering May 12 What It's About: Who cares, really, when it's created by Christopher Guest, the genius behind iconic mockumentaries like This Is Spinal Tap and Best In Show? And when it stars that lovable Irish Everyman Chris O'Dowd (Bridesmaids)? But sure, okay: The plot involves a down-on-his-luck guy who inherits a box of belongings, which spur him to try to uncover his family history. Who will he encounter as he meets with family members? Fred Willard! Ed Begley Jr.! Michael McKean! And several other veterans of Guest's movies! How talented is Christopher Guest? Well, HBO bought his show without even seeing a pilot. So…again, who really cares what it's about?