Anyone know anything about GAD65?

Community Leader
Registered: 09-14-1997
Anyone know anything about GAD65?
7
Fri, 04-12-2013 - 11:08am

My eldest has blood work done and her GAD65 auto antibodies were 3.4. I know that is high, but is it low high, very high? Anyone know?

Avatar for coldfingers
Community Leader
Registered: 04-30-2000
Fri, 04-12-2013 - 7:11pm

I had to look that one up and this is a Mary Frances question for sure! What I found was so full of medical terminology that if Mary Frances isn't familiar she would at least be able to figure it out....

Have they suggested type 1 diabetes? Ruling it out or in?

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Community Leader
Registered: 07-31-1998
Sat, 04-13-2013 - 11:10am

Hi and good morning,

This is one of the tests for MODY (Maturity Onset Diabetes of the Young). It is a type of familial diabetes found in young people (less than 25 y/o). It can be treated with oral medications or with insulin. This is about all I know about this. I would suggest that your eldest be seen by a pediatric endocrinologist ASAP. Maybe this docotr could get to the bottom of what is wrong. Sorry I can't be more helpful.

Community Leader
Registered: 09-14-1997
Sat, 04-13-2013 - 8:51pm

Thanks Ladies. She is actually being evaluated for stiff person syndrome, and her glucose levels are normal. I get so confused with her blood work. Ugh.

Community Leader
Registered: 07-31-1998
Sun, 04-14-2013 - 2:15am

Stiff Person Syndrome is quite rare, even more rare than MODY. The other autoimmune disease that is related to elevated GAD65 is thyroiditis and I know she has had problems with her thyroid. IF she sees a pediatric endocrinologist that person could rule this in or out. Clearly something is going on and I hope they get to the bottom of this soon.

Avatar for coldfingers
Community Leader
Registered: 04-30-2000
Sun, 04-14-2013 - 10:46am

I understand that blood work can be confusing, not being a medical person either. Do you know did they give her an a1c? or just check her glucose randomly?

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Community Leader
Registered: 09-14-1997
Sat, 04-20-2013 - 9:05am

The neuro is ordering the blood work. Her glucose was normal (on the high side) but wasn't a fasting glucose. I don't think they are ordering another glucose test. 

Community Leader
Registered: 07-31-1998
Sun, 04-28-2013 - 2:34am

If it is 200 or above it is diagnostic for diabetes. This is called a randon glucose and it doesn't matter when the person has eaten.