HRT After Menopause Increase Breast Cancer Hazard

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Registered: 01-19-2006
HRT After Menopause Increase Breast Cancer Hazard
Wed, 10-20-2010 - 7:20am

Some upadated findings on this from LiveScience:

Women undergoing hormone therapy for the symptoms of menopause face an increased risk of developing invasive breast cancer or dying of the disease, according to the results of an 11-year study.

Women taking a hormone therapy that uses a combination of estrogen and progestin were 1.25 times more likely to develop invasive breast cancer, and two times more likely to die from breast cancer, than women who took a placebo over the study period.

The study is a follow-up of participants in the Women's Health Initiative, which consisted of several clinical trials involving more than 100,000 women. In 2002, a trial looking at the effects of estrogen and progestin therapy was stopped after 5 and a half years, when researchers found the treatment increased the risk of invasive breast cancer by about 25 percent.

The new study was able to look at the effect of hormone therapy over a longer time period, and was the first to look at a woman's risk of dying from breast cancer.

The findings suggest women taking these hormones should closely follow the current recommendation, which is to use the lowest dose for the shortest amount of time, said study researcher Dr. Rowan Chlebowski, of the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center in Torrance, Calif.

Read more of this article here: Hormones for Menopause Increase Breast Cancer Hazard