Ovarian Cancer Risk & Genetic Markers

iVillage Member
Registered: 01-19-2006
Ovarian Cancer Risk & Genetic Markers
Mon, 09-20-2010 - 8:07am
From LiveScience:

Four variations in a woman's genetic code could put her at a higher risk for ovarian cancer, a new study suggests.

Screening for these particular variations – which occur in about 20 percent of all women – could be vital for prevention and early detection of ovarian cancer, said study researcher Ellen Goode, an epidemiologist at the Mayo Clinic and part of the Ovarian Cancer Association Consortium.

"Eventually, a woman can go to the clinic and, if she has family history, might be given a series of tests to look at changes" to determine if she's at a higher risk for ovarian cancer, Goode told MyHealthNewsDaily.

Ovarian cancer is the eighth most common cancer among women in the United States, and is the fifth leading cause of cancer deaths, according to Centers for Disease Control and Prevention.

The cancer is notoriously difficult to detect in its early stages before it has spread to other organs, but early detection bumps the five-year survival rate to 93 percent, according to the Mayo Clinic.

If women knew their risk, they could get screened earlier for the cancer and take preventive action, Goode said. For example, if a woman knew she was at high risk, she might decide to have her ovaries removed as a precautionary measure.

In the study, scientists from around the world examined the genes of nearly 24,000 women to find genetic variations – called single-nucleotide polymorphisms – that are associated with cancer risk.

The researchers found four genetic variations that were associated with a high risk for ovarian cancer. Having all four meant a higher risk than just having one variation, Goode said.

Read more of this article here:

Ovarian Cancer Risk Tied to Four Genetic Markers


Basking in the wonder of spring...

iVillage Member
Registered: 10-23-2009
Mon, 09-20-2010 - 3:18pm
Thanks for posting this, Nenu! This is promising news indeed, and in combination with other studies of early screening techniques that are currently under way it could lead to a much higher survival rate for ovarian cancer.