Update on Injectable Methotrexate

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Registered: 11-03-2003
Update on Injectable Methotrexate
Tue, 10-04-2005 - 1:57pm

Below is the latest (as of September 8, 2005) information on the injectable MTX shortage.


Methotrexate Injection
Strength: 25 mg/mL, 1 g powder vials
Comment: Methotrexate injection is in short supply because of manufacturing delays. American Pharmaceutical Partners has all products on back order, and expects product will be available in October 2005. APP has no estimated release date for its 1 gram preservative-free lyophilized powder vials. Bedford has all presentations of its 25 mg/mL preservative-free injection available (2-mL, 4-mL, 8-mL, and 10-mL vials). Bedford also has a 1 gram preservative-free lyophilized powder vial available (NDC 55390-0143-01). Mayne has supplies of US-labeled methotrexate in 25 mg/mL 2-mL vials (with preservative, NDC 61703-0350-38) and 25 mg/mL 40-mL vials (preservative-free, NDC 61703-0408-41). Mayne's 20 mg and 1 g preservative-free lyophilized powder vials are unavailable with no release date. (09/8/05, University of Utah, Drug Information Service)


Lyophilized means freeze-dried.

Molly
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