On HIV and BF
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|Fri, 04-04-2003 - 8:23pm|
"FROZEN HUMAN MILK
It is hypothesized that freezing affects lipids in human milk by
down fat globule membranes, decreasing the size of the fat globules,
therefore increasing the surface available for lipase activity.
there is some loss of immunological components during freezing, which
destroys living cells in the milk, some remain intact, and frozen
milk provides more advantages to the infant than commercially
cow's milk based formulas.
In 1989 it was reported that another enveloped virus, similar to the
virus, the human T-cell leukemia virus type 1 (HTLV-1 virus), which is
also spread through blood, sexual activity and breastfeeding ,and which
also nearly always fatal, is killed when human milk is frozen to -20
degrees C (0 degrees F) and thawed. Thus a mother who is HTLV+ may
use this "freeze-and-thaw" method of feeding her own expressed
to her baby. (Ando et al, l989) In a study done to determine the
of pasteurization of human milk, it was found that cell-free HIV was
destroyed after sitting at O degrees C for 30 minutes and the titer of
infected cells was considerably reduced (Orloff et al 1993).
We need to know whether freezing and thawing will also kill the HIV
virus. If so, previously frozen and thawed breastmilk would provide a
safer alternative to formula feeding for the HIV-infected mother with
access to a refrigerator/freezer.
Ando Y, Kakimoto K, Tanigawa T, Furuki K, Saito K, Nakano S, Hashimoto
Moriyama I, Ichijo M Toyama T 1989, Effect of freeze-thawing breast
on vertical HTLV-1 transmission from seropositive mothers to children.
J Cancer Res 80:405-07.
Orloff SL, Wallingford JC, McDougal JS 1993, Inactivation of human
immunodeficiency virus type 1 in human milk: effects of intrinsic
in human milk and of pasteurization. J Hum Lact 9(1):13-17."