2 new genetic links predispose...
Find a Conversation
2 new genetic links predispose...
| Mon, 02-19-2007 - 10:50am |
DH sent me a link to this article...hope my link works. ;-)
www.cbc.ca/technology/story/2007/02/18/autism.html#skip300x250
Amy


I read that somewhere else too.
Sad
What are families to do, not have kids? I wish they would re eval the whole spectrum process. The whole 60 minutes show with the baby banging the lid of the can. Come on already, if you muted the show and showed to someone who doesn't know "autism" would see NOTHING wrong with that baby.
I did agree with the whole not responding to his name. My son did that.
Me and my dh have decided it's not worth trying for a 2nd child. Reading this and watching all these "findings" were the knife in my heart.
God Bless all of you who have more that one child on the spectrum
Nora
http://i153.photobucket.com/albums/s225/irishwildrose/pp2.jpg
Amy,
Do you or anyone have links to more details on these links?
visit my blog at www.onesickmother.com
Paula~
Alas, I'm afraid I don't have any other info. I want to spend some time researching the research (ha!), but wasn't able to get around to it today. If I find anything, I'll send it your way.
Nora~
There was a time, shortly after our youngest (spectrum kiddo #2) was Dx'd that I felt the same way about having more children. But the joy our children bring makes it all worth while...so we're trying for #4. We know that in doing so there's a good chance we'll have another spectrum kiddo. But in my mind, our two spectrum kiddos have made the world a better place, and they've made me a better person...so if a 4th child should be Dx'd with an ASD, I'd feel blessed, yet again.
Amy
Amy
Good for you. My dh is so freaked out it would cause more harm than good in my home. Lord knows we have had a roller coaster life for almost two years. I am taking it hard. He's been very vocal that he doesn't want another child cause "its' not fair to do this to another child, and if the next is NT is it fair they have to take care of Adam later in life"
Rough huh?
Yeah, I am a strong woman who has had a pretty rough childhood and now contending to this life. Sigh, I love my ds with my soul and I'd NEVER trade him. I honestly think we will adopt in a few years. My dh had mentioned that to me cause I do want a sib for my ds.
I feel like I am in this hellish nightmare and cant' get out. My depression has gotten worse and I have NO support other than my sisters here on IVillage.
I got back on my meds for now and hope to find time for a shrink.
Adding insult to injury, my cousin just had a baby, our sons are just nine days apart, and another friend is prego now. So it hurts, more than I can really express.
Thanks and God Bless. Best wishes
Nora
http://i153.photobucket.com/albums/s225/irishwildrose/pp2.jpg
~~~Paula
I got this off the Autism Speaks web site. I saw something on Yahoo news too...........
//////////////////////////////////////////////////////////////////////////////////////////Autism Speaks and the World's Leading Autism Experts Announce the Publication of the Autism Genome Project Phase 1 Results
Preliminary Results of the Autism Genome Project Published in Nature Genetics NEW YORK, NY (February 18, 2007) -- Autism Speaks , a non-profit organization dedicated to increasing awareness of autism and raising money to fund autism research , together with an international consortium of researchers and participating families, today announced the publication of the preliminary results from the largest-ever autism genome scan in Nature Genetics, one of the world's most prestigious research publications.
This research was performed by over 120 scientists from more than 50 institutions representing 19 countries who formed a first-of-its-kind autism genetics consortium, the Autism Genome Project (AGP). The AGP began in 2002 when researchers from around the world decided to come together and share their samples, data, and expertise to facilitate the identification of autism susceptibility genes. The first phase of the effort, the assembly of the largest autism DNA collection ever and whole genome linkage scan, was funded by Autism Speaks and the U.S. National Institutes of Health. The launch of phase two of the project, building on the success of the linkage scan, is being announced in ten days.
The consortium leveraged the unprecedented statistical power generated by its unique sample set by using “gene chip” technology to look for genetic commonality in autistic individuals culled from almost 1,200 families. One third of the DNA and clinical data was provided by the Autism Genetic Resource Exchange (AGRE). The AGP also scanned DNA from these families for copy number variations (CNV), or sub-microscopic genomic insertions and deletions that scientists believe might be involved with this and other common diseases. The innovative combination of these two approaches implicates a previously unidentified region of chromosome 11, and neurexin 1, a member of a family of genes believed to be important in neuronal contact and communication, among other regions and genes in the genome. The neurexin finding in particular highlights a special group of neurons, called glutamate neurons, and the genes affecting their development and function, suggesting they play a critical role in autism spectrum disorders.
“By combining cutting edge CNV analysis with the more traditional linkage and association , the scientists now have a promising new experimental framework to look for autism susceptibility genes,” said Andy Shih, Autism Speaks chief science officer. “These exciting findings from the AGP linkage scan confirm the value and contribution of multidisciplinary collaboration to advancing autism research.”
The AGP Consortium believes the identification of susceptibility genes will provide profound new insight into the basis of autism offering a route to breakthroughs in diagnosis and new treatments in support of families.
ABOUT AUTISM
Autism is a complex brain disorder that inhibits a person's ability to communicate and develop social relationships, and is often accompanied by extreme behavioral challenges. Autism Spectrum Disorders are diagnosed in one in 150 children in the United States, affecting four times as many boys as girls. The diagnosis of autism has increased tenfold in the last decade. The Centers for Disease Control and Prevention have called autism a national public health crisis whose cause and cure remain unknown.
ABOUT AUTISM SPEAKS
Autism Speaks is dedicated to increasing awareness of autism spectrum disorders, to funding research into the causes, prevention, treatments and cure for autism, and to advocating for the needs of affected families. It was founded in February 2005 by Suzanne and Bob Wright, the grandparents of a child with autism. Bob Wright is Vice Chairman, General Electric, and served as chief executive officer of NBC for more than twenty years. Autism Speaks has merged with both the National Alliance for Autism Research (NAAR) and Cure Autism Now (CAN), bringing together the nation's three leading autism advocacy organizations. To learn more about Autism Speaks, please visit www.autismspeaks.org. Autism Speaks UK is chaired by Dame Stephanie Shirley and works closely with the U.S. on research and awareness issues. To learn more about Autism Speaks UK, please visit www.autismspeaks.org.uk. back to top or previous page Autism Speaks International Privacy Terms of Service Contact Us
http://i153.photobucket.com/albums/s225/irishwildrose/pp2.jpg
I wonder if the research is that which has been done by AGRE. It is a project where families with more than one ASD child give blood for genetic research. The whole family donates including the ASD kiddos. We never did it due to SOMEONES extreme fear of needles. But they do an eval and history on the kids too to make sure they meet their criteria, etc.
Renee
We're on "the list" for AGRE...but they haven't managed to get their people to the Peoria area, yet. Every few months we get a letter stating they haven't forgotten about us, and eventually they'll be here to do the blood draws, etc.
Amy
Nora,
Thanks for this.
I am particularly interested as recently, our family has been identified as having a couple of genetic abnormalities: specifically Hereditary Hemochromatosis
visit my blog at www.onesickmother.com
I had that question too. All the new statistics and all the "new" lables. It's getting out of hand here. The 60 show and too much info crammed into too short of time.
Anyhow, I was saying to dh let's see in 10-15 years how this will play out.
The M I N D institue's website had their studies listed on what they are doing.
I dunno, I just take it one day as it comes.
Need to do dinner now, sigh
nora
http://i153.photobucket.com/albums/s225/irishwildrose/pp2.jpg