How many mom's are RH negative? Research

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Registered: 05-16-2006
How many mom's are RH negative? Research
13
Sat, 03-03-2007 - 3:58pm

I came across this on AutismSpeaks.com
I was blown away. I didn't know this was an area that they were researching. I actually have chills and got really sick reading this.
I fall under some of the areas they are looking at. I was given a partial Rogam shot after my miscarriage back in Janurary. I am totally freaking out if I do get pregnant again. My DH is a O positive and I O negative, DS was O positive so I had a 2nd Rogam shot after I delivered him. I had my 1st dose about 7 months into my pregnancy.

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Since 2001, the California Center for Autism and Developmental Disabilities Research and Epidemiology (CA CADDRE) has been one of the largest, most extensive datasets of information on children with autism living in California. CA CADDRE, funded by the Centers for Disease Control and Prevention, is run collaboratively by Dr. Croen from Kaiser Permanente's Division of Research and Drs. Grether and Windham from the Department of Health Services. The CA CADDRE center has also used Kaiser Permanente medical records to investigate autism risk factors during pregnancy and early childhood.

This grant will fund several new analyses of this rich dataset to examine risk factors for autism that have been speculated about in the literature. For example, Dr. Croen and her colleagues will investigate the risk of autism from:

prenatal exposure to the immunization RhoGAM, which is given to women who deliver a Rh+ baby;
maternal illnesses such as infections, inflammation and endocrine disorders;
maternal hormone use, ultrasound exams and maternal use of the asthma drug terbutaline;
maternal exposure to environmental chemicals, including airborne chemicals and workplace exposure.
What this means for people with autism: Data from this study will fill important gaps in understanding environmental risk factors for autism spectrum disorders. Researchers will be able to use the results from these analyses to design future autism studies and, potentially, to design strategies to prevent autism spectrum disorders

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iVillage Member
Registered: 07-06-2006
Sat, 03-03-2007 - 9:04pm

I am Rh-. My first 2 kids have negative types too, but #3 has positive. I had the normal shots with the first 2, but 3 while I was pregnant with #3. I had some complications when I was pregnant with #3, most likely because of the difference in -/+. He has global delays and sensory issues, but we don't *think* he is on the spectrum, he's almost 2. Hayden is the middle child, and on the spectrum, as you all know.

Chrissy




Edited 3/3/2007 9:15 pm ET by chrise-k

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iVillage Member
Registered: 04-06-2005
Sat, 03-03-2007 - 9:05pm

I am B- and my husband is O+. All 3 of my children have been + blood type and I have had one miscarriage. It did occur to me to think about the RhoGAM shots after I read that they contain thimerisol, while reading Evidence of Harm a few years back. My middle child had a double whammy of RhoGAM, too becuz I had some bleeding in 2nd trimester and we wanted to make sure baby would be protected. I know your sick feeling...I've had that, too. And my two boys (2nd and 3rd children) are both on the spectrum. My daughter, and first child, is NT, and honestly the most social beast on the planet, but she was late-ish to talk (only 5 words at 22 months, although she caught up between ages 2 and 3 and won't shut up nowadays).

I will have to look into this study. I've always sort of wondered why they would tell pregnant women to limit intake of tuna and other predatory fish because of mercury risk, but inject any amount of thermisol into them multiple times during pregnancy. Especially since the type of mercury in thimerisol is so much more easily absorbed into the body than the mercury you would find in fish.

Any other Negative blood type Moms out there?
Gemma

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Registered: 09-13-2006
Sat, 03-03-2007 - 10:13pm

DH and I

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Registered: 03-26-2003
Sat, 03-03-2007 - 10:23pm

If you are both O+ then the kids should be that as well. They get it from one of the parents or they may mix. So if one was A+ and the other O- it is possible to have an A- or O+ is my understanding.

That said, DH is A+ and I am O- (universal donor. Blood bank is on my trail!). The kids all took after daddy and are A+ and I have also had 3 misscarriages so more rhogam shots than I can count. My first 2 are spectrum kids, my last 2 are not. Rhogam with the lot.

I don't think you have to freak out over the rhogam you got when preggers. I think it is just one avenue of investigation when they are looking prenatal stuff along with alot of other stuff. The general consensus is our kids are predetermined to have a higher risk and then there is some environmental insult. They are looking into all possibilities but my personal feeling is that there are tons of environmental assaults our kids can't handle. Some we can control and some we can't unfortunately.

Honestly, if you weigh the Rhogam shot of the definite effects if you don't get the shot vs. the maybe possibility of perhaps some kind of ASD if you do...Well I would get the Rhogam shot again in a heartbeat.

Renee

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Registered: 12-22-2003
Sun, 03-04-2007 - 12:08am

Man...we're NEVER going to fit into one of these categories!

DH and I are both A+, as are all three of our kids. No Rhogram. Oldest is on the spectrum, middle is NT, youngest is on the spectrum.

Amy

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Avatar for kingalex
iVillage Member
Registered: 03-27-2003
Sun, 03-04-2007 - 9:11am

I am O- as well. I had a miscarriage about 10 months before getting pregnant with Alex, so I had rhogam shots when I had the miscarriage, and during the pregnancy with Alex. DH is positive, as is Alex.

Very interesting correlation...

Laurie

iVillage Member
Registered: 04-11-2003
Sun, 03-04-2007 - 11:05am

I'm not RH negative. There is a poll on the A-M yahoo group about this topic as well:

Responses
Choices Votes % 1 reply
I am RH negative and received rhogham 67 63
I am not RH negative 39 36

Samantha

Samantha
iVillage Member
Registered: 07-12-2005
Sun, 03-04-2007 - 4:05pm

We fit in with Amy... we'll never fit into this nice little catagory. I'm RH+ and so are both my DH and XH. All of the kids are also RH+. In fact, all of the kids are the same blood type as me (A+). Never had to worry about any of that.

~Candes

APOV on Autism

iVillage Member
Registered: 02-21-2006
Mon, 03-05-2007 - 11:57am

Hi...

I am RH- (A-). My ex-h is B+.

Both of the boys are A+. I wondered about that Rhogam shot all along. I had a miscarriage 1 mo before I conceived my 1st and they gave me the rhogam shot. In fact I had 2 previous miscarriages, but having endometriosis they call them spontaneous abortions. Because I didn't "report" them to the doctor until much later, no confirmatory testing was done. The last miscarriage I had we were able to confirm through bloodwork that I had been pregnant. They immediately gave me the Rhogam, and cautioned me that because we believed I had miscarried twice before without receiving hte shot I may have difficulty bringing a pregnancy to full-term. UGH>>> they make you question everything, you know?

For a long time I faulted myself for not being careful NOT to get pregnant after my 3rd miscarriage...they like you to wait 3 or more months, but we weren't trying... It was Valentine's day and the only one of 2 days the entire month we saw each other!!! Now I can blame myself another way!

Nicole

iVillage Member
Registered: 03-25-2003
Mon, 03-05-2007 - 6:21pm

Interesting. My son, PDD-NOS & ADHD, is B+. My dh B+ (?) and I'm A-. I had the Rhogam shot twice with him.

However, whether the Rhogam injection was the cause or not, I have no regrets. The pros of the Rhogam injections out weigh the cons by far.

Shell




Edited 3/5/2007 6:26 pm ET by dragonfly_shell

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