I failed the CCCT.... I HATE THIS!!!

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iVillage Member
Registered: 01-15-2007
I failed the CCCT.... I HATE THIS!!!
Wed, 11-12-2008 - 5:10pm

So after three weeks of trauma and surprise and devastation, I find out the results of my clomid challenge test and it was bad. My FSH level is still staggeringly high and I am devastated. My GYN is now referring me to an RE who I hope will agree to try to treat me. For those of you who don't know know what the problem with high FSH is I have copied and pasted some info that I fell is very helpful. Thanks for reading!

"One of the most frustrating problems in IVF today is that of poor ovarian response. This is also known as poor ovarian function, poor ovarian reserve, occult ovarian failure, or the oopause. It’s well known that pregnancy rates in IVF are directly dependent upon the quality and number of embryos transferred, and the more the eggs a woman grows, the better the embryos we can select from. This is why women with a good ovarian response have much higher pregnancy rates than women with a poor ovarian response.

Usually, ovarian functions goes hand in hand with age, and as a women becomes older, her ovarian response starts declining. Every girl is born with a finite number of eggs, and their number progressively declines with age. A measure of the remaining number of eggs in the ovary is called the "ovarian reserve"; and as the woman ages, her ovarian reserve gets depleted. The infertility specialist is really not interested in the woman's calendar (or chronological age), but rather her biological age - or how many eggs are left in her ovaries.

Various tests have been described to measure ovarian reserve. The commonest test measures the level of FSH ( follicle stimulating hormone) in the blood - the basal ( day 3) FSH level. A high level suggests poor ovarian reserve; and a very high level ( more than 20 mIU/ml, though this varies from lab to lab ) is diagnostic of ovarian failure. A test that can provide earlier evidence of declining ovarian function is the clomiphene citrate challenge test ( CCCT). This is similar to a " stress test " of the ovary; and involves measuring a basal Day 3 FSH level; and a Day 10 FSH level, after administering 100 mg of clomiphene citrate from Day 5 to Day 9. If the sum of the FSH levels is more than 25, then this suggests poor ovarian function, and predicts that the woman is likely to have a poor ovarian response ( she will most probably grow few eggs, of poor quality) when superovulated. Remember that a high FSH level does not mean that you cannot get pregnant - it just means that your chances are dropping because your egg quality is impaired."

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iVillage Member
Registered: 01-08-2008
Wed, 11-12-2008 - 5:16pm
i am so sorry. (((hugs))) IF is so frustrating and devastating. i think it's a good idea to get a referral to an RE. if you want to see the ivf success rates for clinics in your area, the cdc's website has the data. some centers are very choosy about their patients so their stats can be high, but there are many good RE's that will treat more complicated cases (one clinic near us has low stats b/c they have a lot of patients who have failed ivf cycles elsewhere). we're here for you!


TTC since Sept '06. Diagnosed w/ PCOS, DH diagnosed with azoospermia Dec '06, TESA Mar '07
IVF/ICSI/AZH#1 Aug'07, BFN (6 usable eggs, 5 embies, 2 transferred, 1st beta=18, 2nd beta=12, 0 made it to blast to freeze)
IVF/ICSI#2:retrieval Nov'07 (w/ fresh TESA), FET sched Jan'08, no embryos to transfer (23 usable eggs, 12 embies, 0 made it to transfer)
IVF/ICSI#3: retrieval Mar'08, FET May'08, BFN (13 usable eggs, 7 fertilized w/ DH sperm= 0 blasts, 6 fertlized w/ DS=3 blasts, all 3 transferred, 1st beta=74, 2nd beta=64, 3rd beta=42)
1st cycle IUI/clomid/donor sperm postponed due to lack of follicular growth on 100mg clomidx5days.


mom to beautiful baby lia.
iVillage Member
Registered: 05-20-2008
Wed, 11-12-2008 - 5:27pm
(((HUGS))) I also failed my CCCT, but it is still possible to concieve with high FSH.


iVillage Member
Registered: 06-28-2008
Wed, 11-12-2008 - 7:51pm
Tons of (((((((((((HUGS)))))))))))))
iVillage Member
Registered: 03-17-2008
Thu, 11-13-2008 - 8:09am


I am sorry about the CCCT. I don't know how old you are, but many women have had success with DHEA (get the micronized kind at the health food store). DHEA is used by older women who have trouble with egg quality. The normal starting dose is 25mg and I've heard of people going up to 75mg. You can google DHEA or check out the TTC over 40 DHEA section.

DHEA does not work for people with PCOS however. There are a lot of women with high FSH who have had positive results with it and attribute their pregnancies to it. I have heard of people having a rapid heart beat but they are a small minority. I started taking it in oct. I'm not sure yet if it is having an effect because I won't be BDing until Dec when my husband comes home from Iraq.

I wish you luck.



Waiting for DH to come home to try again!

In the meantime, herbs and prayers

Check out my fertility blogs at http://soldierinstirrups.blogspot.com/

Franklin and Callan

iVillage Member
Registered: 10-31-2008
Thu, 11-13-2008 - 9:13am
I'm so sorry you are going through this.


TTC since 6/2007. 
IVF #1 Jan 2009 - BFN
IVF# 2  April 2009 - BFN
IVF# 3 July

iVillage Member
Registered: 10-31-2008
Thu, 11-13-2008 - 10:59am
Gigantic Hugs Jen.