Implantation failure testing HELP?

iVillage Member
Registered: 10-28-2009
Implantation failure testing HELP?
5
Tue, 04-03-2012 - 3:49pm

I would like any and all suggestions on the below issue!!

I have had 2 previous ectopic pregnancies that thrived, perfect betas, even saw a heartbeat with one. I have had 3 uterine pregnancies that were the exact opposite, one empty sac, 2 chemical pregnancies. I am convinced that there is something wrong in my uterus. Is that crazy? I feel like something is keeping these embies from thriving in there. I just can't believe that it's "bad luck" and not a medically explainable thing! I have had a large fibroid removed 3 years ago. I also have tested homozygous MTHFR but with normal homocysteine levels (so no treatement) and I have antithyroid antibodies which I'm on low dose synthroid for. Do you guys have any suggestions for what I should be tested for? I feel like my RE just wants to keep trying and I want to make sure we have covered all bases before my third and likely final IVF. These are a few that I have emailed my RE that I would like, any more suggestions? clotting issues, hysteroscopy/D&C, mycoplasm, etc.

My RE doesn't put much stock in immune testing, so not sure if I should even go down that road.

-Jamie

iVillage Member
Registered: 09-06-2004
Tue, 04-10-2012 - 10:03pm
I have been lurking & cheering you on. I am sorry i do not post much. It sounds like your RE is similar to mine. I was thinking - could you talk to a mfm dr now about your history if your RE is not open to new things. They are knowledgeable. They might recommend putting you on lovenox right away. I had a friend with mthfr & after 5 years got pg, her dr put her on lovenox right away. She also did the intralipids. I think she had to fight to do this and may have used an out of town dr to do so. She had a sticky pg with these things. I am cheering you on & wishing you the best!!!
iVillage Member
Registered: 01-11-2008
Tue, 04-10-2012 - 11:59am

Jamie - I think in most cases it isn't that you can't carry, just have to find out the magic solution.

----"Never give up on something that you can't stop thinking about every second of every day."----

Chris 

iVillage Member
Registered: 10-28-2009
Sat, 04-07-2012 - 10:01pm
Thanks Crazy08, that's a really helpful website.
Leslie, its so good to hear from you! I've been taking baby aspirin since my diagnosis with MTHFR. I started taking it in my own, my RE did not recommend it. Oddly the first month I was on it was the first month I ever got pg (ectopic).
I just feel like I'm at that point of wondering whether I will ever be able to carry a child. After this next fresh which is already paid for, we likely would try donor embryos or move on to adoption. We cant keep throwing money at IVF. I'm just fearful that even with perfect embryos my uterus will still reject them. And maybe I'm just over analyzing everything and I've just had some dud embryos causing the chemicals, but we're desperate at this point and really want to feel like we tried everything possible.

-Jamie

iVillage Member
Registered: 09-06-2004
Sat, 04-07-2012 - 9:35pm
Have you taken baby aspirin during your cycles? I had 2 Chemical pregnancies and my RE did not believe in testing for immune issues. I decided based on a recommendation from a friend on my own to take baby aspirin starting about 6 weeks before my successful cycle with my little boy. My betas on this cycle were very low but I truly believe it was the baby aspirin that helped me. And due to a blot clot scare during my pregnancy, I learned I too had homozygous mthfr with normal homosysteine levels as well as abnormal results for a lupus anticoagulant and protein c something or other. Baby aspirin has seemed to help me so I thought I would recommend if you have not tried yet.

The other suggestion is to call an RE who specializes in immune testing even if they are out of town for a consultation. They may be able to suggest & work with you to get testing done if your RE will not.

I am thinking of you.
iVillage Member
Registered: 01-11-2008
Tue, 04-03-2012 - 4:49pm

This link may help.. look around this blog and see what you can find.. I know a lot of RE's do not believe in immune dysfunction but a lot of gals who have had miscarriages and chemical pregnancies have had live births after doing intralipid therapy.

----"Never give up on something that you can't stop thinking about every second of every day."----

Chris