Just got my protocol - which drugs worked for you?

iVillage Member
Registered: 10-05-2012
Just got my protocol - which drugs worked for you?
8
Wed, 10-17-2012 - 1:05pm

I've been trying to do some prep for my IVF coming up in the next few weeks and I just got a laundry list of drugs today and I wanted to find out your opinions of them... and to ask what the heck they are for! My class is next Tuesday, so I'm sure I'll learn a lot then. But of course I'm too impatiend to wait an entire week. Wink

I'm going to be on:

Menopur
Ganirelix
Bervelle (sp?)
Hepren
Zithromax (antibiotic for 4 days)
Avadril
Progesterone
Sesame oil 

Which of those is the injectibles? Is Follistem missing from that list? Is that just a given in all protocols? What on earth is the significance of sesame oil? Thank you so much for your help, ladies!

iVillage Member
Registered: 10-05-2012

... and after a 2-second Google search I see now that I misspelled some of those so let me correct that...

Heparin
Ovidril 

iVillage Member
Registered: 02-29-2000

Follistim is an stimulating drug, but it is one of many, so not everyone uses it. Here's a breakdown with a little info on each of the meds in your list.

Menopur - is a stimulating drug and comes in a package with a vial of water and a vial of powder. You draw out water and mix with the powder and then it's given in a subcutaneous injection. It does not require refrigeration.

Ganirelix - this drug is used to prevent ovulation and most likely will come in prefilled syringes. Also subcutaneous and I believe this one does need to be refrigerated.

Bravelle - this is also a stimulating drug (has a little different formulation than the menopur, so that is why you probably are doing both). I believe it is packaged similar to the menopur where you draw up a certain amount of water and mix with a powder. It is also a subcutaneous injection.

Heparin - this is a blood thinner and I believe used to help increase blood flow to the uterus. I believe it is a subcutaneous injections as well, but I never used that so don't have as much info.

Zithromax - the antibiotics are used to reduce the likelihood of infection from all the procedures. pretty standard practice.

Ovidrel - this is an hcg trigger drug. you will be given a specific time to take this one that will be 36 hours before retrieval. It is a pre-filled syringe and taken subcutaneously as well.

Progesterone in Oil (PIO) - This is where the sesame oil is, it isn't a stand alone item. This one is the most fun (not) of all the meds. It is an intramuscular injection taken in the hip. Starting the day of retrieval and going through at least beta (but hopefully 9 - 10 weeks), it provides additional progesterone support to helps sustain an environment to support pregnancy. There are things to make this shot a lot easier, but sometimes it can quite literally be a pain in the butt. But worth it for you end result!! I didn't have a lot of trouble with this one, myself, but some people do. Definitely take a look at some of the tips as you get closer to retrieval to find things that make this one easier to do.

Hope that helps!

iVillage Member
Registered: 08-26-2008

So exciting to have your protocol =) Cilla already gave you lots of good info so I'll just add a couple tid-bits. Every doctor has preferences for certain meds based on their own experiences of what works best. It looks like your doctor has you on Menopur and Bravelle for stimulation instead of Follistim. I also took those and they worked great for me. Most of these are injectables, all except for the Zithromax from what I see. The progesterone might be in the sesame oil, I don't know that you would take that alone for any reason. Please keep us posted on how your class goes. When do you start stims?

Caryn

iVillage Member
Registered: 10-05-2012

I'm not really sure at this point. I stop taking BCPs on the 26th, wait for AF to arrive, and report to the doc's office on cycle day 3. I'm assuming I will learn about when to start stims in my shot class next week. When is the typical time to start them?

iVillage Member
Registered: 10-28-2009
Hi there welcome to the board ! I believe the bravelle and menapur are ur stims I've never used them though I used follistim but u don't have to every protocol is different progesterone in sesame oil ... Sesame oil isn't given by itself simply the median the progesterone is in :) heparin is a blood thinner and ganirelix prevents ovulation after a few days on stims. When are u starting ur cycle ?
iVillage Member
Registered: 10-05-2012

My last day of BCP is this Friday! Getting really excited! I know this sounds dumb, but I've been fighting this urge to start walking through baby departments again. After our last miscarraige, I completely warned off baby stuff. I'm terrified to go see little clothes and little beds and little everything and let myself fall in love with the concept all over again. When is it okay to start letting yourself be optimistic again? I am so scared of letting my guard down and this not working and being a mess all over again... 

iVillage Member
Registered: 02-29-2000
Okay, I have to admit when I was cycling that I went and bought one little outfit for boy and one for a girl and I hung them up where I could see them to be my inspiration. (I don't know what your faith is, so please don't be offended by this mention, but I also prayed that one or both of those little outfits would be filled.) It's okay to be cautiously optimistic. You have to let yourself believe in some small part that you will succeed. Don't go wild, but it's okay to have hope. You have to have that to get through all the emotional highs and lows of IVF.
iVillage Member
Registered: 10-05-2012

I did that too the last time we were pregnant! As soon as I found out, I went out and bought a few cute little outfits for a boy and a girl. We miscarried a few weeks later and I just put the clothes and all the books in a box and shoved them in the back of a closet. I've been thinking about them lately and wondering if I should throw the clothes away. They kind of feel like they were for, well, another baby. I actually kind of like the idea of buying clothes and praying for a baby to fill them. I found this quote last night when I was flipping through inspriational internet quotes (which I generally don't like), and I found this: In answer to the question, What is the difference between bravery and courage, one little boy answered, "Bravery is doing something you are afraid of. Courage is being smart enough to know you are afraid of something and doing it anyway."