Michelle - E2 expert!

iVillage Member
Registered: 11-27-2007
Michelle - E2 expert!
7
Fri, 08-13-2010 - 9:05am

So I only got half my bloodwork back yesterday. The first time they took blood (CD2) they didn't take enough so I had to go back yesterday (CD3) and get more drawn. So I'm not 100% sure which tests are from what days (just to make things more complicated). I should be getting back results on my testosterone, progesterone, CBC, thyroid, and blood sugars today or Monday.

So the ones I got back yesterday I think are from CD2:
hcg - <2 (obviously... not surprised)
E2 - 66
FSH - 4.5

Now I know the FSH is a good number. Insurance won't cover any treatment if it's above 19 and I've read that it should be above 3. She said that the E2 was "perfect" but I don't know what E2 is or where it needs to be or even what it does. Any wisdom to bestow on me about this?

PS. What does Metformin do exactly? I have the script and she said to wait to fill it until we get the rest of the results but I'm contemplating filling it anyway cause I don't think it would hurt anything to try it.

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iVillage Member
Registered: 07-28-2009
Fri, 08-13-2010 - 9:15am

Yes, that IS a perfect resting E2 level, girl! And what I mean by resting is that your E2 level is at it lowest at the beginning of your cycle. As you FSH increases and your follicles start to mature, your E2 level should be about 200 per mature follicle. By the E2 is just fancy for Estrogen.


So most women will have an E2 level at about 200 when they O. Mine was over 2800 at the end of my last medicated cycle.


Here is GREAT link I used to use to check my levels of all kinds of stuff:


http://www.fertilityplus.org/faq/hormonelevels.html#female


Here is the range for E2 at the beginning of your cycle:






Estradiol (E2)
Day 3
25-75 pg/ml
Levels on the lower end tend to be better for stimulating. Abnormally high levels on day 3 may indicate existence of a functional cyst or diminished ovarian reserve.

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iVillage Member
Registered: 11-27-2007
Fri, 08-13-2010 - 10:04am

Thanks! I think I found that site when I was looking yesterday afternoon. I was just unsure on what E2 actually meant. Thanks for explaining, that makes sense. I guess they will check that again when I go for the u/s and b/w if I get a +OPK before CD17.

And what has your experience been on Metformin? I have a friend on another board who got pregnant on that and progesterone supplements after having repeat chems.

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iVillage Member
Registered: 07-28-2009
Fri, 08-13-2010 - 11:17am

Oh yes I forgot to reply to the Metformin question. Metformin is primarily used as a Glucophage (sp?) for people with Diabetes. It's regulates the body's processing of insulin. As you know, Insulin resistance is a HUGE symptom of PCOS and is very good at reducing the chance of early m/c and also aides conception even in women without insulin resistance as it has been shown to improve eqq quality in some studies which would potentially combat chromosomal issues.


It also helps a lot of women lose some weight! LOL Make sureeeeee you take it with food at least for the first few weeks. You'll totally end up on the toilet for hours with a numb heiny if you don't! LOL

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iVillage Member
Registered: 11-27-2007
Fri, 08-13-2010 - 12:04pm
ROFL. Thanks for the warning. The nurse did say to only take one tablet a day for the first week and then go up to two. Taking food with it is not something she suggested, but I will keep that in mind. Thanks a lot! I think I will go get that filled today even if she says I don't need it.

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iVillage Member
Registered: 12-08-2009
Fri, 08-13-2010 - 12:13pm
Ohhhhh E2 means ESTROGEN! LOL I had no idea either.
Michelle, I love how you are so knowledgeable about this stuff, so that you can help to educate the rest of us!


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iVillage Member
Registered: 11-27-2007
Fri, 08-13-2010 - 3:35pm
So I filled the prescription. Would you believe it was only $4 for a 30 day supply?! And I have 6 refills available. Yeah, I'll be trying this out for a little while since it doesn't seem like it could hurt anything. Bloodwork from yesterday isn't back yet, so they'll probably call me about it on Monday. Thanks for all the advice!

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iVillage Member
Registered: 07-28-2009
Fri, 08-13-2010 - 5:34pm
Oh yeah! It's cheap as all get out! You can get it here at Publix for free!

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