BFP and strong betas!

iVillage Member
Registered: 10-19-2004
BFP and strong betas!
15
Mon, 12-21-2009 - 12:37pm

(cross posted on TTCYFC 6+ months)

Hi ladies,

After 3+ years and 7 losses TTC our first child, this BFP is looking like strongest and most "normal" yet!

I got my beta results back and they are:

12dpo: 58
14dpo: 157

That's a doubling time of 33.4 hours.

With the twins, my 12 dpo beta was 72 and 14dpo was 130. These are the only 2 pregnancies that have had a 14dpo beta over 50.

With this pg, my hpt's started getting darker at 9dpo.

I'll post all the nitty-gritty details because I know some of you like to see this stuff.

What we did: This cycle we did IUI using an IVF protocol with BCP's and lupron. 225 foll/75 menopur stim days 1-3, 150/75 stim days 4-10. At m request, after seeing this study, w e added co-stimulation with HGH (Human Growth Hormone- Omnitrope) on stim day 5, 8IUI/day through the day after trigger.

http://humrep.oxfordjournals.org/cgi/content/full/20/9/2536

I also started taking Metformin. This was after getting a second opinion from Dr. Robert Greene at SIRM that I did have a form of PCOS despite the fact I have regular peiods. I have PCO-type ovaries based on follicle counts, and infertility 3+ years. The Metformin may reduce my m/c risk and could help egg quality issues caused by PCO.

IUI timing and stats: We pushed back the timing of IUI a bit based on some reasearch I'd read. Due to a snafu at our clinic we ended up doing 2 IUI's, one at 39 hours with my DH's sperm, about 36 million motile 53% motility after the wash. (Before the wash motility was 32%- his highest ever). This was DH's best sperm results ever...he's had as low as 6 million. The only thing really different I had him do was start taking 1,000 mg vitamin B12 based on a study I read. He's had a problem with immature sperm.

http://www.andrologyjournal.org/cgi/content/full/28/4/521

The second IUI was at 40 hours with about 13 million motile donor sperm. That was out insurance policy, as DH's sperm has shown profound problems on some sophisticated tests beyond just motility...3% morph, 22% HDS/immature sperm chromatin on SCSA diagnostics test, and 40% non binding sperm in hyaluonan test (out of normal looking motile sperm that would be selected for ICSI), and poor embryo development and arrest before and especially after day 3 in split test ICSI studies (not seen with donor sperm). We have never had evidence of natural fert with my DH's sperm.

So a total of almost 50 million motile sperm!

Other things I did that were not different included eating watermelon in follicular phase, pineapple and brazil nuts in luteal phase, acupuncture in late follicular phase, after IUI and around implabation, and in luteal phase. I had DH eat Gogi berries throughout my follicular phase, and eat lots of lycopene rich foods (tomatoes). He also took acetyl-l carnitine. I had him ad d some l-carnitine this cycle as well, so combined he was getting a higher dose of this supplement that some studies show can improve motility- so though he'd been on it before the dosage was higher.

I took it pretty easy during the cycle after stim day 5 (my last gym workout). Ate lots of organic food, whole grains, healthy high- antioxidant foods.

And of course we had my fibroid that was distorting the shape of my uterus removed with a hysterscopic myomectomy back in July, that was a possible factor in some of my losses. My uterine contous now looks normal.

Trigger day follie counts:

Left ovary: 20.42, 18.66, 18.64, 18.1, 17.55, 17.38, 16.54, 14.84, 13.83, 13.72

Right ovary: 22.16, 21.4, 17.94, 17.46, 17.35, 15.33, 14.1, 13.71, 13.68, 12.92, 11.38

Dr said there were 5+ other follies 12-14mm he did not bother to measure (by the time he did that many on left it was clear I would trigger that day anyway).

On stim day 10 my lining was 11mm triple stripe.

I triggered on Stim day 11, after 10 days of stims.

So that's the scoop on what we did. I've had increasingly darker lines since 9dpiui. Last night I had a bit of scare when I did one with aftrenoon urine and it looked like a BFN until much later, even then a very light line. 2 other FRER's also produces very light lines. I think it was a defective test. I did an Equate test with the same sample and that was a clear an immediate BFP, as was a CBE ovulation test I used. I mention because I'd never experienced that with FRER's before. I opened a new box this am and the test was fine, darker than yesterday. Getting close to the control line color today at 15dpiui.

Anyway after everything we've been though and our losses of the twins at 9-10 weeks and 16 weeks with a chromosomal abnormality and my water breaking after amnio, obviously we won't be able to "relax" or be really confident for a long time even if things look good. But so far so good, and I think this has as good of a chance of turning into an actual baby or two as anything we've seen yet at this stage.

Wish me luck, we really need it! We would be thrilled with a healthy singleton or twins. I have been told it is not likely that I could successfully carry triplets.

I'll get my bext beta on Tuesday and will get the results on Wednesday. I don't know when my first u/s will be yet. -Jenna, 41, DH 38 TTC our first since September '06 with MFI.




Edited 12/21/2009 12:58 pm ET by jennagreen
- Jenna

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iVillage Member
Registered: 10-20-2009
Mon, 12-21-2009 - 12:54pm

Jenna:


Wow - that's a lot of information!

Susan L.



Robert Edward Xavier Lin - Born July 31, 2010 at 5:56AM, 6 pounds 4 ounces and 19 inches long. He spent 2 weeks in the NICU but he's doing great now!
iVillage Member
Registered: 05-31-2004
Mon, 12-21-2009 - 1:11pm
Congratulations! That is absolutely awesome! I am not usually on here until later in the day, but I had to see if you had posted! :-) Thanks for all the info, great information. You have certainly done everything you can, that is a LOT to keep track of! I am looking forward to hearing how your pregnancy progresses, and just how many are growing in there! With my 14 yr old we were told there were 5 very mature eggs sitting there, and were given the option to skip that cycle but we went ahead and only had one. Now we often wonder just what we would have done if all 5 had conceived! Lol! I hope it is only one or two so that you don't have to face further worries or complications. So happy for you!

Michelle


Loving Mom to three

Michelle


Loving Mom to three rambunctious 

iVillage Member
Registered: 09-13-2007
Mon, 12-21-2009 - 3:27pm
Congrats Jenna, that was a long time coming.
 


 


Susan V

iVillage Member
Registered: 06-26-2009
Mon, 12-21-2009 - 5:42pm

Jenna,


Congrats on the BFP news and thanks for sharing all the information. I have printed the HGH article for my RE.

iVillage Member
Registered: 08-17-2007
Tue, 12-22-2009 - 10:38am
Jenna, that is awesome news! Congrats on the terrific numbers. HH9M!

Susan CB



TTC #1

Starting first (and with any luck, last) IVF cycle in early 2010


Susan CB

iVillage Member
Registered: 01-17-2007
Tue, 12-22-2009 - 7:06pm
MERRY CHRISTMAS!!!!! BIG HUGS AND CONGRAT"S JENNA!!! it's been a long time coming :) SBV's coming for you girl...







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iVillage Member
Registered: 05-28-2008
Wed, 12-23-2009 - 10:35am

Jenna, a big big congrats to you! awesome news and what a great time of year to get it on!!! I'm glad the numbers are looking promising! Enjoy the holidays!!!! and keep us posted! SBVs as well

Lynda



 

iVillage Member
Registered: 05-31-2004
Sun, 12-27-2009 - 3:49am
So Jenna, how did your last beta go? I trust all is still going well and you are just having a wonderful time celebrating both your good news and Christmas to post any results! :-)

Michelle


Loving Mom to three

Michelle


Loving Mom to three rambunctious 

iVillage Member
Registered: 10-19-2004
Mon, 12-28-2009 - 5:36pm

Thanks ladies for all the support!

Kristi I hope this cyycle works and you don't need to do anything further, but I can tell you I am a true believer in HGH now!

Michelle, My RE's office to my suprise said I didn't need any more betas and should just get a u/s at 7 weeks. I did one anyway though at 16dpo and it was great, 379, way more than double the previous one of 157.

All is well here. No more spotting since the implantation spotting at 11dpo. Vomiting about daily for the past week or so. I did another beta just for reassurance today at 22dpo but I expect it will be fine. Took an HPT today and test line is now much darker than control.

U/s will be late afternoon Jan 11th. I'll be 7w1d. A long time to wait!

- Jenna, 41, DH 38 TTC since September '06 with MFI. 3 failed unmedicated IUI's with DH sperm, 1 failed IUI with injects with DH sperm, IVF #1 BFN, FET BFP but M/c week 5, IVF#2 BFP m/c week 7, IUI with injects and donor sperm: probable chemical pg. 1 failed unmedicated DS/IUI. Started BCP's 7/30 for IVF #3, ER 9/10, ET 9/15, Beta 9/24 results 9/25. BFP, Twins. Lost 1st twin at 9-10 weeks, lost second twin at 16 weeks 12/17/08. Attempted IUI #4 converted to DS/DH IUI April 09 at my request, BFP and M/c. IVF #4 June 09 BFN. DS-IUI w/injects 7/6/09, BFN. Hysteroscopic myomectomy to remove fibroid 7/29/09.Unmedicated DS-IUI 9/09, BFN. DS-IUI with injects, 10/09, BFP and M/C. DH/DS-IUI with injects and HGH, 12/6, beta 12-20.
- Jenna
iVillage Member
Registered: 05-31-2004
Tue, 12-29-2009 - 2:28am
I am so glad things are going well for you this time. :-) I know how nerve wracking it can be after even one loss let alone what you have gone through. I hope the time until your u/s passes quicker than you are expecting it to! And do post the results of you beta when you can. :-)

Michelle


Loving Mom to three

Michelle


Loving Mom to three rambunctious 

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