Well, I finally had my CD 3 blood work done today.
Hope your numbers come back with good news!
That was really interesting info. But now I have a question for those of you who have done the clomid challenge. What exactly do they test you for? My doctor never really did that, but he did measure my progesterone after ovulation (cd 21, 23, 25) Is the clomid challenge related to what the AMH shows? Can you tell how many eggs were developed by progesterone levels after ovulation? Just wondering, since he didn't do any other tests. I am okay with that, it isn't like we are planning to do anything extra at this point anyway. I am just curious since it seems my progesterone was quite high if I remember right.
Loving Mom to three
Loving Mom to three rambunctious
I just looked this up- here is what was said. I have high AMH levels and we think the reason why is because I did not have cycles for many years (over 15 years) due to nursing children. I would only ovulate when they turned 3 due to them night nursing keeping my fertility low and hence a good egg reserve LOL.
AMH levels assess ovarian reserve Recently, a new hormone marker, anti-Müllerian hormone (AMH), has been evaluated as a marker of ovarian reserve. AMH is produced solely in the granulosa cells of small ovarian follicles. Recent reports indicate that AMH levels decline with increasing female age and that initial AMH is associated with ovarian response in IVF patients with normal FSH levels. AMH levels seem to correlate with other measures of ovarian reserve such as the the antral follicle count or FSH level. Serum AMH levels from women are lower than those in men throughout life. One potential advantage of using AMH as a marker of ovarian reserve is that it does not seem to change over the course of the menstrual cycle. FSH, on the other hand, must be measure on Day 2 or Day 3 of the menstrual cycle or on Day 10 if it is drawn as part of a clomid challenge test.
Most commercial labs are not accustomed to determining AMH levels on fertility patients. The cutoff values for normal should therefore be determined by the fertility doctor based on the outcomes of the patients.
For example, percentile ranking can determine where a particular patient's levels fall in relation to other women with infertility or women with known good fertility (such as egg donors). At IVF1, as of December 2007, 95% of infertile women have an AMH level higher than 0.365. The 50th percentile or mean level is the point at which 1/2 of the patients have higher levels and 1/2 have lower levels. The 50th percentile for AMH is 2.48. The highest level seen in our practice to date is an AMH level of 10.
We have counseled women who have an AMH level in the bottom 5 to 10 percent that they have significantly decreased ovarian reserve.
I don't have PCOS, but it did say one's levels are higher with PCOS.
I didn't get a cycle from the time I was 27 years old (when I got preggo with number 3) until 3 years ago- all due to pregnancy/nursing. I got pregnant without getting a cycle back several times because I *caught* the first egg. I had ditched charting years prior to that and only relied on cervical mucous and how open the OS was. Now that I have had cycles for past 3 years I am unable to pin-point all this now ARGH!!!!
Hmmm...I wish I knew my AMH score, since I have PCOS and basically never cycle without the help of meds. I've routinely gone up to 4-6 months without a period for several years at a time.
It actually got somewhat better after my first pregnancy, and then better still (but still irregular) after the 2nd.
TTC#3 since June 2010. Me = 39 w/ PCOS; DH = 43; married 13 years.Taking: Pre-natal, 100mg B6, 50mg Clomid, Robutussin#1Clomid baby, born 2003. Aaron! #2Clomid baby, lost to heart defect in 2nd trimester, 2006
My Ovulation Chart
Very, very interesting.
Happy to help! AMH blood test is definitely newer and less common--fewer labs do this test, and it's costly, so some places bypass it. But unlike FSH, the level rarely fluctuates wildly and you can do the test on ANY day of your cycle. More docs are relying on it as an indicator of how far you are from menopause/level of ovarian reserve. Anything between 1 and 3 is considered ideal range, but of course, docs take all your numbers into consideration, so one "off" number isn't necessarily cause for panic.
So yeah, the basics now for your reproductive profile are:
Day 2-3 FSH/Estradiol, etc bloodwork.Day 2-3 Antral Follicle Count (so far, I've only done a resting one, not on Day 3) via vaginal sonogram.AMH blood test.HSG/SIS test--one or the other. Two types of sonogram/xray they do to check the shape/condition of your uterus/tubes
they may ask for other stuff, too, but this seems to be the Gold Standard of basic info an RE will want.
At least that's been consistent for me in shopping around. But because my situation will involve IVF (husband had a vasectomy that we don't want to reverse for various reasons, so we'd need to do sperm aspiration, which only works with IVF, not IUI), I may go to OverKill Doctors, as far as information. :)