new, clueless, w/genetic test question

iVillage Member
Registered: 03-04-2005
new, clueless, w/genetic test question
7
Wed, 01-11-2006 - 2:29pm

Hi everyone,

I'm 41 with a 1-year-old DS. DH wants to have another (I'm in favor of adopting) but even if we were able to conceive, we're looking at a minimum maternal age of 43. DH thinks there are genetic testing methods out there that can determine whether an egg would have problems (without destroying the egg, obviouslY) but I've never heard of any.

Does anyone know?

TIA!

iVillage Member
Registered: 11-30-2004
Wed, 01-11-2006 - 11:06pm

I have the same question and an appt with my RE on Fri to discuss this, among other issues! I will let you know what I find out!!

kim

iVillage Member
Registered: 03-04-2005
Thu, 01-12-2006 - 7:58am

Very cool, thank you! Also I left a message with my old ob/gyn (great dr. -- but we moved to a new town after she delivered DS) in the hope that she'd be updated on the latest research, etc.

It seems like modern medicine is accomplishing amazing things these days (women in their 50s and even 60s having healthy babies) but at the same time, the kinds of procedures we mere mortals are able to get seem so primitive. With DS I kept trying to find out about a maternal blood test that can be done instead of the amnio and they kept telling me it was decades away from being practical....

Thanks and GL!

iVillage Member
Registered: 04-05-2004
Thu, 01-12-2006 - 9:13am

Hello Ladies
Yes, there is a procedure you can have done to insure a genetically good embryo. The procedure is IVF with PGD (preimplantation genetic diagnosis). It is only done with in-vitro. They fertilize the egg and remove a cell on day three and check for many chromosome abnormalities, then they only insert the normal embryos. The whole thing seems so unbelievable and a bit scary. I am seriously thinking of doing it, however it is expensive and you do run the risk at our age of not having any good eggs. Unfortunaltey, I recently lost a son at 16 weeks due to trisomy 21 (down syndrome) and I could never go through that pain again. Having a miscarriage is one thing, been there done that 3 times, but to carry a child for 16 weeks is another.
Hope this helped.

Marisol 40
DH 41
DS 9
DS 7
DD 5

iVillage Member
Registered: 11-30-2004
Thu, 01-12-2006 - 11:10am

thank you so much for posting this, I am going to ask my dr about this Fri. when you say expensive, what are we talking, IVF is already costing us a small fortune, but it is our only option.

kim

iVillage Member
Registered: 03-04-2005
Thu, 01-12-2006 - 11:16am

Thanks! That makes a lot of sense, they've got the fertilized egg right there, why couldn't they run tests on it.

(Really clueless) Do you know how much that procedure runs (with IVF -- I don't know anything about the costs of that either) and whether insurance tends to cover the test and IVF?

Condolences on your loss, it must have been terrible. I went through agonies having the amnio done on DS -- I was so afraid we'd be the 1 in 200 that miscarried due to the procedure. Can't imagine how it would have felt if DS hadn't been 100% fine.....

Thanks again!

iVillage Member
Registered: 04-05-2004
Thu, 01-12-2006 - 2:19pm
Hi
With my fertility group. they charge an additional $5000 for the PGD and since I am over 40 my HMO may not cover any of it.
Marisol
iVillage Member
Registered: 10-13-2004
Thu, 01-12-2006 - 3:50pm

Hi, Poorcow. Welcome!


Just one more thing about PGD: You need to produce enough embryos to have it done because the procedure itself can be hard on the embies and it's possible to lose them. I think they like to have at least six to do PGD.


The irony of it all is that even though PGD is often recommended for over-40 moms, we very often can't produce enough embryos



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