My sister in law has been trying since she was 39 to get pregnant. She is now 42 with 4 failed IVF's under their belt.Her and her DH were out of money for IVF but could afford to pay for a few IUI's. Obviously alot less medication and medical expense. In the past 3 years her doctor did all kinds of tests and could never actually find any reason for infertility except for her age, he agreed to give the IUI's a try. Today she called me with her very first BFP at 42!!!!!!!