Hi, I'm really confused about these new boards, I hope I am still on the pain support board! I was supposed to start taking Cymbalta for my very chronic back pain and fibro. I had already talked to a pharmacist about the Arthrotec. He said to watch for bruising or bleeding, but that it should be O.K. My hope was that after a period of time, the Cymbalta would work and I could go off the Arthrotec. So, now I'm ready to start the Cymbalta and it suddenly occurred to me did my doctor think about interactions between effexor and cymbalta. She thought I should stay on the effexor (37.5) because it was probably helping with hot flashes, which are minimal for me. I haven't had a period in almost a year, and my hot flashes are almost non-existant, so I thought this was a good idea! Now though, I've been reading and I'm scared to take the two together. I've spoken to a pharmicist, and he thinks it may or may not be a problem taking them together. He thought I could try it and see what happens. I also have a call in to my doctor, waiting to hear back from them. I am also scared to take Cymbalta! I am reading about all the bad side effects and am thinking is it better to just be in pain because I am used to it!!!! I don't want sweat running from my head, etc., and all these crazy things I'm reading about! To top off my stress level right now, I think I forgot to take my effexor yesterday because today I'm feeling really crappy and just want to go lay down and not get up again. I took it about an hour ago, so hopefully in the next hour or two I'll feel better because I have to go to work! I'll have to do more reading about the Cymbalta. I had read that it really helped people with their pain. I read more people were helped by it than were bothered by the side effects. Now I'm reading people had horrible bad effects from taking it, and I just don't know what to do!!! I used to take Wellbutrin and the effexor together. Life was pretty good, except for my pain!!!!!! I went off the Wellbutrin to go on the Cymbalta. I haven't noticed any decrease or increase in my pain, but I do feel more tired lately, so I think I need the anti-depressant. Anyhow, I am babbling and I feel crappy so I'm going to let my dog out to pee and go lay down again. Any advice would be appreciated!