Frontotemporal dementia is a group of diseases in which parts of the brain (the frontal and temporal lobes) shrink, or atrophy, causing changes in personality and behavior. People with frontotemporal dementia may display unusual behavior, such as a lack of caring and lack of inhibition.

In one type of frontotemporal dementia, called Pick's disease or Pick's complex, abnormal structures called Pick's bodies develop in brain cells. Pick's disease is rare but can run in families.

People with frontotemporal dementia may:

• Not express any caring for others.
• Not attend to personal hygiene.
• Say rude things to others, expose themselves, or make sexually explicit comments, or exhibit other socially inappropriate behavior.
• Be obsessed with repetitive routines or develop unusual food obsessions, such as eating the same kind of food or eating in the same restaurant repeatedly.
• Have difficulty understanding words and naming objects.

Frontotemporal dementia cannot be reversed. Doctors may treat its associated behavioral problems with antidepressants and other medications.

By	Healthwise Staff
Primary Medical Reviewer	Kathleen Romito, MD - Family Medicine
Specialist Medical Reviewer	Peter J. Whitehouse, MD - Neurology
Last Revised	June 17, 2009