Gonadotropin-Releasing Hormone Analogues for Infertility

 

GnRH analogues (agonists and antagonists) predictably stop ovulation and menstruation. Agonists take more days of treatment than antagonists do to shut down the ovaries.

Controlling ovulation timing before an infertility procedure. Shutting down the pituitary with GnRH analogue treatment, paired with a hormone to stimulate egg production, lowers the chance that an ART procedure will be canceled because of early ovulation. For controlling egg production before an infertility treatment, a longer course of GnRH agonist treatment has been shown to produce higher pregnancy and live birth rates, when compared with a short course of doses.1

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