Gonadotropin Treatment for Infertility

 
Generic Name Brand Name
human chorionic gonadotropin (hCG) Ovidrel (prescription), Pregnyl (prescription)
human menopausal gonadotropin (hMG) Bravelle (prescription), Repronex (prescription)
recombinant human follicle-stimulating hormone (rFSH) Follistim (prescription), Gonal-F (prescription)

The body produces two types of gonadotropins: follicle-stimulating hormone (FSH) and luteinizing hormone (LH). After they are produced by the pituitary gland, gonadotropins trigger production of other sex hormones. Gonadotropins therefore play a part in egg and sperm production, as well as female and male physical traits such as voice, muscle, hair, and breast development.

Human menopausal gonadotropin (hMG) and recombinant human follicle-stimulating hormone (rFSH) are gonadotropin fertility drugs.

  • hMG contains natural FSH and LH, purified from urine from postmenopausal women. (After menopause, women produce high levels of gonadotropins, which are excreted in their urine.)
  • rFSH is genetically synthesized in the laboratory.

Human chorionic gonadotropin (hCG) is similar to LH. It contains equal amounts of LH and FSH. These hormones play a central role in egg production.

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