Gymnema

 
Gymnema
Common names:
Gurmar, Gurmarbooti
Botanical names:
Gymnema sylvestre

Parts Used & Where Grown

Gymnema sylvestre is a woody climbing plant that grows in the tropical forests of central and southern India. The leaves are used in herbal medicine preparations. G. sylvestre is known as "periploca of the woods" in English and meshasringi (meaning “ram’s horn”) in Sanskrit. The leaves, when chewed, interfere with the ability to taste sweetness, which explains the Hindi name gurmar—“destroyer of sugar.”

What Are "Star" Ratings?

a7_3star Reliable and relatively consistent scientific data showing a substantial health benefit.

a7_2star Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.

a7_1star For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:


Used for AmountWhy
Type 1 Diabetes
800 mg per day of an herbal extract standardized for 25% gymnemic acids2 stars Gymnema may help normalize blood sugar control in people with type 1 diabetes.

2 stars Type 1 Diabetes

800 mg per day of an herbal extract standardized for 25% gymnemic acids

Test tube and animal studies have found several mechanisms by which gymnema may help normalize blood sugar control in diabetics.1 In a controlled trial with people with type 1 diabetes, 400 mg per day of gymnema extract reduced requirements for insulin.2 Whether the extract used in this study was standardized for active constituents is unclear. Recently, a preliminary trial found improved blood sugar levels after three months in a group of people with type 1 and type 2 diabetes who took 800 mg per day of an extract standardized for 25% gymnemic acids.3 Gymnema is not a substitute for insulin, but insulin amounts may need to be lowered in order to avoid hypoglycemia while taking gymnema.

Used for AmountWhy
Type 2 Diabetes
800 mg daily of an herbal extract standardized for 25% gymnemic acids2 stars Gymnema may stimulate the pancreas to produce insulin and may help normalize blood sugar control in people with diabetes.

2 stars Type 2 Diabetes

800 mg daily of an herbal extract standardized for 25% gymnemic acids

Gymnema may stimulate the pancreas to produce insulin in people with type 2 diabetes. Gymnema also improves the ability of insulin to lower blood sugar in people with both type 1 and type 2 diabetes. So far, no double-blind trials have confirmed the efficacy of gymnema for people with any type of diabetes. However, a preliminary study of type 2 diabetics reported that 400 mg per day of gymnema extract taken for periods of 18 months or longer resulted in improvement, according to diabetes blood tests, and allowed reduction of diabetic medications.4 In a controlled trial with type 1 (insulin-dependent) diabetics, a similar amount of gymnema extract reduced requirements for insulin.5 Whether the extract used in these studies was standardized for active constituents is unclear. Recently, a preliminary trial found improved blood sugar levels after three months in a group of type 1 and type 2 diabetics who took 800 mg per day of an extract standardized for 25% gymnemic acids.6 Gymnema is not a substitute for insulin, but insulin amounts may need to be lowered while taking gymnema to avoid hypoglycemia.

Traditional Use (May Not Be Supported by Scientific Studies)

Gymnema has been used in India for the treatment of type 1 and type 2 diabetes for over 2,000 years. The leaves were also used for stomach ailments, constipation, water retention, and liver disease.

Also indexed as:
  • botanicals,
  • gurmar,
  • gymnema,
  • Gymnema sylvestre,
  • gymnemic acid,
  • herbal dietary supplements,
  • herbal medicine,
  • herbal remedies,
  • herbal therapy,
  • herbalism,
  • plant Medicine

About this treatment

Common names:
Gurmar, Gurmarbooti
Botanical names:
Gymnema sylvestre

How It Works

The hypoglycemic (blood sugar-lowering) action of gymnema leaves was first documented in the late 1920s. This action is attributed to members of a family of substances called gymnemic acids. Gymnema leaves raise insulin levels, according to research in healthy volunteers. Based on animal studies, this may be due to regeneration of the cells in the pancreas that secrete insulin, or by increasing the flow of insulin from these cells. Other animal research shows that gymnema can also reduce glucose absorption from the intestine, improve uptake of glucose into cells, and prevent adrenal hormones from stimulating the liver to produce glucose, thereby reducing blood sugar levels.

Other animal studies have shown that extracts of gymnema leaves can lower serum cholesterol and triglycerides and prevent weight gain, but these effects have not been tested in humans. When placed directly on the tongue, gurmarin, another constituent of the leaves, and gymnemic acid have been shown to block the ability in humans to taste sweets.

How to Use It

Clinical trials with diabetics in India have used 400 mg per day of a water-soluble acidic fraction of the gymnema leaves. The gymnemic acid content of this extract is not clear. A recent preliminary trial in the United States reported promising results in a group of type 1 and type 2 diabetics who took 800 mg per day of an extract standardized for 25% gymnemic acids. Traditionally, 2 to 4 grams per day of the leaf powder is used.


Last Review: 05-11-2011

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The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2011.

© 1995-2011 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated. This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

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