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Hormone replacement therapy (HRT) refers to the use of estrogen plus progestin for the treatment of perimenopausal symptoms.
Estrogen and progestin combinations (pills or tablets)
| Generic Name | Brand Name |
|---|---|
| conjugated estrogens/medroxyprogesterone | Premphase (prescription), Prempro (prescription) |
| estradiol/norethindrone | Activella (prescription) |
Transdermal combination preparations (a patch placed on the skin that continuously releases estrogen and progestin)
| Generic Name | Brand Name |
|---|---|
| estradiol/norethindrone acetate | CombiPatch (prescription) |
Oral progestin (pills or tablets; used along with an estrogen-only preparation)
| Generic Name | Brand Name |
|---|---|
| medroxyprogesterone | Provera (prescription) |
| micronized progesterone | Prometrium (prescription) |
| norethindrone | Micronor (prescription), Nor-QD (prescription) |
| norethindrone acetate | Aygestin (prescription) |
Progestin intrauterine device (IUD; used along with an estrogen-only preparation)
| Generic Name | Brand Name |
|---|---|
| levonorgestrel | Mirena (prescription) |
Estrogen-progestin hormone therapy, or HRT, is recommended for all women with a uterus who choose to take estrogen. Using estrogen without progestin greatly increases your risk of endometrial cancer. Taking progestin with estrogen eliminates this increased risk.1
| By: | Healthwise Staff | Last Revised: May 4, 2010 |
| Medical Review: | Kathleen Romito, MD - Family Medicine Carla J. Herman, MD, MPH - Geriatric Medicine | |
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