Another sexually charged role, as Maggie Gyllenhaal's S&M-loving boss in 2002's Secretary, earned Spader (pictured in 2009) more critical kudos. But audiences were introduced to a new side of Spader in 2003 when he parlayed his role as lawyer Alan Shore on The Practice into a more lighthearted spin-off titled Boston Legal. Spader's comedic work opposite William Shatner during the show's five-season run earned him critical acclaim: two Emmys, a Golden Globe nomination and four Screen Actors Guild nominations -- to be exact. Most recently, Spader landed a spot on the ever-growing list of potential replacements for Steve Carell on The Office; he'll guest-star on the show's May 19 season finale. Spader has two children with his first wife, Victoria Kheel (the couple divorced in 2004), and welcomed his third child -- a son -- in 2008 (with his Alien Hunter costar Leslie Stefanson). In 2012, he appeared in the movie Lincoln and has already began filming a next movie called The Homesman.