After 20 years of marriage, the Dr. Quinn, Medicine Woman actress is splitting from her fourth husband. The couple said in a statement to US Weekly: "Jane Seymour and James Keach confirm that they are separated and have been for several months. At this time they are negotiating the terms of their divorce." Seymour and Keach share 17-year-old twins John and Christopher. The actress was previously married to Michael Attenborough, Victor Planer and David Flynn. She has two children, Katherine, 31, and Sean, 28, with Flynn.