Significant changes in eating and sleep patterns are symptoms of major depression, and are often linked. This is not surprising, since a common brain circuitry regulates both. The most commonly seen symptom of clinical depression is loss of appetite, resulting in weight loss. Depressed people often report a loss of appetite and interest in food, along with diminished enjoyment in eating. This is paired with insomnia, the inability to fall asleep. Some people can fall asleep but can’t remain asleep, awakening throughout the night with fitful sleep, or rising after only a few hours.