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MSG Sensitivity - References
Enjoy the taste of Chinese food and other ethnic dishes without the headaches and nausea that MSG can sometimes cause. According to research or other evidence, the following self-care steps may be helpful.
- Mix in a B6
Take 50 mg of vitamin B6 a day to help process MSG into harmless byproducts
- Forego certain foods
Check food labels for MSG and ask restaurant staff if the food you eat contains MSG
- Skip the seasoning
Avoid Accent or Aji-No-Moto products and any foods containing these seasonings
Also indexed as:
- monosodium glutamate,
- monosodium glutanate,
- MSG
About this treatment
1. Kwok RHM. Chinese-restaurant syndrome. N Engl J Med 1968;278:796 [letter].
2. Prawirohardjono W, Dwiprahasto I, Astuti I, et al. The administration to Indonesians of monosodium L-glutamate in Indonesian foods: an assessment of adverse reactions in a randomized double-blind, crossover, placebo-controlled study. J Nutr 2000;130(4S Suppl):1074–6S.
3. Bazzano G, D’Elia JA, Olson RE. Monosodium glutamate: feeding of large amounts in man and gerbils. Science 1970;169:1208–9.
4. Morselli PL, Garattini S. Monosodium glutamate and the Chinese restaurant syndrome. Nature 1970;227:611–2.
5. Zanda G, Franciosi P, Tognoni G, et al. A double blind study on the effects of monosodium glutamate in man. Biomedicine 1973;19:202–4.
6. Tung TC, Tung KS. Serum free amino acid levels after oral glutamate intake in infants and human adults. Nutr Rep Int 1980;22:431–43.
7. Schaumburg HH, Byck R, Gerstl R, Mashman JH. Monosodium L-glutamate: its pharmacology and role in the Chinese restaurant syndrome. Science 1969;163:826–8.
8. Rosenblum I, Bradley JD, Coulston F. Single and double blind studies with oral monosodium glutamate in man. Toxicol Appl Pharmacol 1971;18:367–73.
9. Kenney RA, Tidball CS. Human susceptibility to oral monosodium L-glutamate. Am J Clin Nutr 1972;25:140–6.
10. Walker R, Lupien JR. The safety evaluation of monosodium glutamate. J Nutr 2000;130(4S Suppl):1049–52S [review].
11. Geha R, Beiser A, Ren C, et al. Multicenter multiphase double-blind placebo controlled study to evaluate alleged reactions to monosodium glutamate (MSG). J Allergy Clin Immunol 1998;101:S243 [abstract].
12. Geha RS, Beiser A, Ren C, et al. Review of alleged reaction to monosodium glutamate and outcome of a multicenter double-blind placebo-controlled study. J Nutr 2000;130(4S Suppl):1058–62S [review].
13. Stegink LD, Filer LJ Jr, Baker GL. Effect of aspartame and sucrose loading in glutamate-susceptible subjects. Am J Clin Nutr 1981;34:1899–905.
14. Wen CP, Gershoff SN. Effects of dietary vitamin B6 on the utilization of monosodium glutamate by rats. J Nutr 1972;102:835–40.
15. Folkers K, Shizukuishi S, Scudder SL, et al. Biochemical evidence for a deficiency of vitamin B6 in subjects reacting to monosodium-L-glutamate by the Chinese restaurant syndrome. Biochem Biophys Res Commun 1981;100:972–7.
Last Review: 05-11-2011
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The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2011.
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