Policosanol

 
Policosanol

Policosanol is a mixture of long-chain alcohols (waxes), including octacosanol, extracted from natural sources.

What Are "Star" Ratings?

a7_3star Reliable and relatively consistent scientific data showing a substantial health benefit.

a7_2star Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.

a7_1star For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:


Used for AmountWhy
Intermittent Claudication
10 mg twice per day3 stars Supplementing with policosanol may reduce platelet stickiness and improve walking capacity.

3 stars Intermittent Claudication

10 mg twice per day

Policosanol, taken in the amount of 10 mg twice a day for at least six months, increases pain-free walking capacity by over 50% in people with intermittent claudication according to two double-blind trials.1, 2 When policosanol was taken continuously for two years, walking capacity more than doubled.3 This effect may be related to the ability of policosanol to reduce the stickiness of platelets,4, 5, 6 which could result in improved circulation.


Used for AmountWhy
High Triglycerides
10 to 20 mg daily 2 stars Policosanol may be helpful in normalizing triglyceride levels.

2 stars High Triglycerides

10 to 20 mg daily

The effect of policosanol on serum triglycerides has been inconsistent, ranging from no effect up to as much as a 19% reduction.7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 Several controlled studies have compared policosanol with cholesterol-lowering medications, such as statins, and have found policosanol similarly effective.17 , 18 , 19 , 20 , 21 , 22 , 23 Policosanol extracted from beeswax or other sources differs from the sugar-cane-derived preparation in the proportions of long-chain alcohols, and whether these types of policosanol are as effective as sugar-cane-derived policosanol is unknown.


Used for AmountWhy
High Cholesterol
Refer to label instructions 1 star Policosanol may affect cholesterol levels by inhibiting cholesterol production by the liver but most research has casted doubt on its effectiveness.

1 star High Cholesterol

Test tube and animal studies indicate that policosanol is capable of inhibiting cholesterol production by the liver.24 , 25 Extensive preliminary and double-blind research in Cuba and other countries in Latin America has demonstrated that taking 10 to 20 mg per day of policosanol extracted from sugar cane results in significant changes in blood cholesterol levels, including total cholesterol (17 to 21% lower on average), LDL cholesterol (21 to 29% lower), and HDL cholesterol (7 to 29% higher).26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 However, virtually all of this research was conducted by a single research group from Cuba. Follow-up double-blind studies performed in the United States,37 , 38 Canada,39 Italy,40 and Germany41 found that sugar cane-derived policosanol in amounts of 10 to 80 mg per day taken for 12 weeks had no effect on serum cholesterol levels in people with initially high cholesterol levels.  Therefore, it seems doubtful that policosanol has a beneficial effect on serum cholesterol levels.
Also indexed as:
  • policosanol,
  • polycosanol

About this treatment

How to Use It

Most studies have used 5 to 10 mg of policosanol taken twice per day.

Where to Find It

The long-chain alcohols found in policosanol are present in many foods of plant origin. Supplemental policosanol is typically extracted from sugar cane or beeswax.

Possible Deficiencies

Policosanol is not an essential nutrient, so no deficiencies are possible.


Last Review: 05-11-2011

LogoCpyrt.gif

Copyright © 2011 Aisle7. All rights reserved. www.Aisle7.net

Learn more about Aisle7, the company.

The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2011.

© 1995-2011 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated. This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

Advertisement
Care Circle

It Seems That You Are Not Logged In...

OR

Join Now

Welcome to Care Circle, an exclusive tool to help you take care of yourself and your loved ones. Here's how it works:

  1. Create profiles for yourself and your loved ones.
  2. Select the topics and conditions that interest each of you.
  3. Get customized news updates, original content, tools, and expert advice for each Care Circle member delivered directly to your personalized homepage.

The information you input is strictly private; you choose who has access to your Care Circle.

How do I add myself or someone else to my care circle?

Click on "Add someone." Fill out the short profile. Choose an avatar. Select the topics and conditions that interest this person from the pulldown menu. You can select as many as you want, but you must choose at least one. Click on "Add Someone" again. You should start getting updates immediately.

How do I save content to my Care Circle?

Click on "Manage My Care Circle." Select the tab of the person for whom you're saving content. Put your cursor over the piece of content that you want to save; a disk icon will appear in the righthand corner. Click on the disk and the piece of content will be moved to a save folder.

How do I add additional topics and conditions for someone in my Care Circle?

Click on "Manage My Care Circle." Select the tab for the person whose preferences you'd like to update. Under "Add More to Follow," select additional topics and conditions.

How do I delete topics and conditions for someone in my Care Circle?

Click on "Manage My Care Circle." Select the tab for the person whose preferences you'd like to update. Under "Follows," scroll over the topic or condition you want to delete. An "X" should appear on the righthand side. Click on the "X" and the topic or condition will be deleted from the list.