Nobody’s perfect, not even you Rob Lowe (although I think you are). Rob, who last night started a run on the ABC Drama Brothers and Sisters was offered the Patrick Dempsey role of McDreamy on Grey’s Anatomy and turned it down. He told USA Today that it was “the first time in all of my career that I picked wrong … definitely a biggie.” If I remember correctly you've picked wrong before, but I don't want to dwell on the past, Rob, because I still love you. Oh and how cute was Rob on Brothers and Sisters last night? Do you think he's going to be a good addition to an already stellar cast? And by "stellar" I mean so freakin' cute and I'm talking about you, Dave Annable who plays Justin, so delicious to look at!