Sclerotherapy is the most common and, to date, most effective way to get rid of spider veins. A saline solution is injected into a vein, causing it to swell, collapse and then disappear. When blood can't flow, the vein loses its purple color, turns to scar tissue and eventually fades away entirely. Because blood flow shifts to other healthy veins, sclerotherapy actually improves circulation in the legs. The saline injections are often followed by a mild burning sensation and, occasionally, muscle cramping near the site of injection, especially around the ankles. The cramping usually subsides within a few minutes. The site will look swollen and needle marks will show, but these symptoms clear up within two weeks.
Depending on the size, shape and network of your spider veins, a series of three to ten treatments is usually required. Unfortunately, the treatment is not always permanent; about one-third of all women develop spider veins again.