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"Today I witnessed my first grandchild being born, life changing experience," Sharon posted on Twitter Tuesday. "She is an angel."
Jack and his fiancee confirmed April 24 that they had welcomed little Pearl into the famous family, that includes grandpa Ozzie Osbourne and aunt Kelly Osbourne.
Sharon, 59, gave a live Twitter chat Wednesday where she discussed how she feels about becoming a grandmother and adding her newborn granddaughter to the Osbourne clan.
The Talk host, who once said she didn't want to be called "Grandma," even volunteered to take care of the baby.
She wrote, "I will love babysitting b/c with all the wonderful things we're giving away on The Talk on CBS on Friday, I'll be prepared!"
And Grandma isn't the only excited member of the iconic rock family. New aunt Kelly also took to Twitter to discuss the baby's birth.
"Thank you so much for your congratulations but they really should be going to Lisa Stelly and Jack Osbourne! I am one proud Auntie!"