Note: For those of you aware of the dangers of Cytotec (misoprostol), a prostaglandin implicated in high rates of uterine rupture in VBAC labors, the study states that Cytotec had only been introduced in 1996, the last year of the study. The study compares uterine rupture rates with induction involving prostaglandin in the years preceding 1996 with 1996 and finds no difference. I expect this is because Cytotec probably wasn’t in common use in its first year. I venture to predict that if researchers looked at a later year, rupture rates associated with prostaglandin would have climbed even higher than they were during the study years.
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