Wilson’s Disease - References

 
Wilson’s Disease
An excess of copper in the body can lead to a long list of health problems. According to research or other evidence, the following self-care steps may be helpful.
  • Try zinc

    Reduce dietary copper absorption by supplementing with zinc; consult your doctor to determine the correct amount to use

  • Steer clear of copper

    Work with a nutritionist to make sure you avoid eating foods that are high in copper

Also indexed as:
  • hepatolenticular degeneration,
  • Wilsons disease,
  • Wilson's disease

About this treatment

1. Hoogenraad TU, Van den Hammer CJA, Van Hattum J. Effective treatment of Wilson’s disease with oral zinc sulphate: two case reports. Br Med J 1984;289:273–6.

2. Cossack ZT. The efficacy of oral zinc therapy as an alternative to penicillamine for Wilson’s disease. N Engl J Med 1988;318:322–3 [letter/review].

3. Brewer GJ, Dick RD, Johnson VD, et al. Treatment of Wilson’s disease with zinc: XV long-term follow-up studies. J Lab Clin Med 1998;132:264–78.

4. Brewer GJ, Yuzbasiyan-Gurkan V. The use of zinc-copper metabolic interactions in the treatment of Wilson’s disease. J Am Coll Nutr 1989;8:452 [abstract 103].

5. Hoogenraad TU. Zinc treatment of Wilson’s Disease. J Lab Clin Med 1998;132:240–1 [editorial].

6. Brewer GJ, Hill GM, Dick RD, et al. Treatment of Wilson’s disease with zinc. III. Prevention of reaccumulation of hepatic copper. J Lab Clin Med 1987;109:526–31.

7. Brewer GJ, Yuzbasiyan-Gurkan V. Use of zinc-copper metabolic interactions in the treatment of Wilson’s disease. J Am Coll Nutr 1990;9:487–91.

8. Brewer JG, Yuzbasiyan-Gurkan V, Lee D-Y, Appelman H. Treatment of Wilson’s disease with zinc. VI. Initial treatment studies. J Lab Clin Med 1989;114:633–8.

9. Van den Hamer CJA, Hoogenraad TU. Copper deficiency in Wilson’s disease. Lancet 1989;ii:442 [letter].

10. Van Caillie-Bertrand M, Degenhart HJ, Visser HKA, et al. Oral zinc sulphates for Wilson’s disease. Arch Dis Child 1985;60:656–9.

11. Brewer JG, Yuzbasiyan-Gurkan V, Lee D-Y, Appelman H. Treatment of Wilson’s disease with zinc. VI. Initial treatment studies. J Lab Clin Med 1989;114:633–8.

12. Brewer GJ, Johnson VD, Dick RD, et al. Treatment of Wilson’s disease with zinc. XVII: treatment during pregnancy. Hepatology 2000;31:364–70.


Last Review: 05-11-2011

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The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2011.

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